Potassium Citrate Dosage
This dosage information may not include all the information needed to use Potassium Citrate safely and effectively. See additional information for Potassium Citrate.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Nephrolithiasis
Initial:
If urinary citrate is less than 150 mg/day: 60 mEq/day (30 mEq two times/day , 20 mEq three times/day, or 15 mEq four times/day) orally with meals or within 30 minutes after meals or bedtime snack.
If urinary citrate is greater than 150 mg/day: 30 mEq/day (15 mEq two times/day or 10 mEq three times/day) orally with meals or within 30 minutes after meals or bedtime snack.
Maximum dosage: 100 mEq/day
Usual Adult Dose for Renal Tubular Acidosis
Initial:
If urinary citrate is less than 150 mg/day: 60 mEq/day (30 mEq two times/day , 20 mEq three times/day, or 15 mEq four times/day) orally with meals or within 30 minutes after meals or bedtime snack.
If urinary citrate is greater than 150 mg/day: 30 mEq/day (15 mEq two times/day or 10 mEq three times/day) orally with meals or within 30 minutes after meals or bedtime snack.
Maximum dosage: 100 mEq/day
Usual Pediatric Dose for Nephrolithiasis
Study (n=8)
9.7 +/- 1.2 years: 2 mEq/kg/day in three divided doses, then titrated upwards, at 2 months intervals, to 3 mEq/kg/day, and to a final dose of 4 mEq/kg/day.
Usual Pediatric Dose for Renal Tubular Acidosis
Study (n=8)
9.7 +/- 1.2 years: 2 mEq/kg/day in three divided doses, then titrated upwards, at 2 months intervals, to 3 mEq/kg/day, and to a final dose of 4 mEq/kg/day.
Renal Dose Adjustments
The use of potassium citrate in patients with chronic renal failure should be avoided due to the risk of hyperkalemia and cardiac arrest.
Liver Dose Adjustments
Data not available
Dose Adjustments
Dosage changes should occur after evaluation of results from twenty-four hour urinary citrate and/or urinary pH measurements.
Measure urinary pH and/or urinary citrate every 4 months during duration of therapy in adults.
Precautions
Treatment should be discontinued if there is hyperkalemia, a significant rise in serum creatinine, or a significant fall in blood hematocrit or hemoglobin. Serum electrolytes (sodium, potassium, chloride and carbon dioxide), serum creatinine, and complete blood count should be monitored every four months.
Dialysis
Data not available
Other Comments
Potassium citrate is used to restore normal urinary citrate (320 mg/day and as close to the normal mean of 640 mg/day), and to increase urinary pH to a level of 6.0 to 7.0.
Patients should be encouraged to drink plenty of fluids per day, to reach a goal of at least 2 liters of urine per day.
