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Posaconazole Dosage

Medically reviewed by Drugs.com. Last updated on Jul 4, 2023.

Applies to the following strengths: 40 mg/mL; 300 mg; 100 mg; 18 mg/mL

Usual Adult Dose for Aspergillosis - Invasive

PROPHYLAXIS OF INVASIVE ASPERGILLUS AND CANDIDA INFECTIONS:
IV:


ORAL:
Delayed-Release Tablets:

Oral Suspension: 200 mg orally 3 times a day

Duration of Therapy:

TREATMENT OF INVASIVE ASPERGILLOSIS:
IV:

ORAL:
Delayed-Release Tablets:

Duration of Therapy:

Comments:

Uses:

Usual Adult Dose for Candidemia

PROPHYLAXIS OF INVASIVE ASPERGILLUS AND CANDIDA INFECTIONS:
IV:


ORAL:
Delayed-Release Tablets:

Oral Suspension: 200 mg orally 3 times a day

Duration of Therapy:

TREATMENT OF INVASIVE ASPERGILLOSIS:
IV:

ORAL:
Delayed-Release Tablets:

Duration of Therapy:

Comments:

Uses:

Usual Adult Dose for Oral Thrush

Oral Suspension:
Oropharyngeal candidiasis:


Oropharyngeal candidiasis refractory to itraconazole and/or fluconazole: 400 mg orally twice a day

Use: For the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole

Usual Pediatric Dose for Aspergillosis - Invasive

PROPHYLAXIS OF INVASIVE ASPERGILLUS AND CANDIDA INFECTIONS:
IV:
2 to less than 18 years:


ORAL:
Delayed-Release Tablets:
2 to less than 18 years, weighing greater than 40 kg:

Oral Suspension:
13 to less than 18 years: 200 mg orally 3 times a day

Powder for Delayed-Release Oral Suspension:
2 to less than 18 years, weighing 10 to 40 kg:

Duration of Therapy: Should be based on recovery from immunosuppression or neutropenia

TREATMENT OF INVASIVE ASPERGILLOSIS:
13 to less than 18 years (regardless of weight):
IV:

ORAL:
Delayed-Release Tablets:

Duration of Therapy:

Comments:

Uses:

Usual Pediatric Dose for Candidemia

PROPHYLAXIS OF INVASIVE ASPERGILLUS AND CANDIDA INFECTIONS:
IV:
2 to less than 18 years:


ORAL:
Delayed-Release Tablets:
2 to less than 18 years, weighing greater than 40 kg:

Oral Suspension:
13 to less than 18 years: 200 mg orally 3 times a day

Powder for Delayed-Release Oral Suspension:
2 to less than 18 years, weighing 10 to 40 kg:

Duration of Therapy: Should be based on recovery from immunosuppression or neutropenia

TREATMENT OF INVASIVE ASPERGILLOSIS:
13 to less than 18 years (regardless of weight):
IV:

ORAL:
Delayed-Release Tablets:

Duration of Therapy:

Comments:

Uses:

Usual Pediatric Dose for Oral Thrush

Oral Suspension:
13 to less than 18 years:
Oropharyngeal candidiasis:


Oropharyngeal candidiasis refractory to itraconazole and/or fluconazole: 400 mg orally twice a day

Use: For the treatment of oropharyngeal candidiasis, including oropharyngeal candidiasis refractory to itraconazole and/or fluconazole

Renal Dose Adjustments

IV:


Oral:

Comments:

Liver Dose Adjustments

Mild to severe liver dysfunction (Child-Pugh A, B, or C): No adjustment recommended.

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 2 years.

Consult WARNINGS section for additional precautions.

Dialysis

This drug is not removed by hemodialysis.

Other Comments

Administration advice:
IV:

ORAL:

Storage requirements:

Reconstitution/preparation techniques:

IV compatibility:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.