Phenylephrine/Pyrilamine Dosage

Usual Adult Dose for Allergic Rhinitis

phenylephrine-pyrilamine 25 mg-60 mg oral tablet:
1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 20 mg-16 mg oral tablet, chewable, extended release:
1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 5 mg-16 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 9 mg-12 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours as needed, not to exceed 20 mL in 24 hours.

phenylephrine-pyrilamine 10 mg-25 mg oral tablet:
1 tablet orally every 4 to 6 hours, not to exceed 6 tablets in 24 hours.

phenylephrine-pyrilamine 10 mg-30 mg/5 mL oral liquid:
5 mL orally every 6 to 8 hours as needed, not to exceed 25 mL in 24 hours.

Usual Adult Dose for Cold Symptoms

phenylephrine-pyrilamine 25 mg-60 mg oral tablet:
1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 20 mg-16 mg oral tablet, chewable, extended release:
1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 5 mg-16 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 9 mg-12 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours as needed, not to exceed 20 mL in 24 hours.

phenylephrine-pyrilamine 10 mg-25 mg oral tablet:
1 tablet orally every 4 to 6 hours, not to exceed 6 tablets in 24 hours.

phenylephrine-pyrilamine 10 mg-30 mg/5 mL oral liquid:
5 mL orally every 6 to 8 hours as needed, not to exceed 25 mL in 24 hours.

Usual Pediatric Dose for Allergic Rhinitis

phenylephrine-pyrilamine 5 mg-16 mg/5 mL oral suspension, extended release:
phenylephrine-pyrilamine 12.5 mg-30 mg/5 mL oral suspension:
2 years to 5 years: 2.5 mL orally every 12 hours as needed.
6 years to 11 years: 5 mL orally every 12 hours as needed.
12 years or older: 5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 12.5 mg-30 mg oral tablet, chewable:
2 years to 5 years: 1/2 tablet orally every 12 hours as needed.
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years or older: 1 to 2 tablet orally every 12 hours as needed.

phenylephrine-pyrilamine 5 mg-30 mg/5 mL oral suspension:
2 years to 5 years: 2.5 to 5 mL orally every 12 hours as needed.
6 years or older: 5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 25 mg-60 mg oral tablet:
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years or older: 1 to 2 tablet orally every 12 hours as needed.

phenylephrine-pyrilamine 10 mg-16 mg oral tablet, chewable, extended release:
2 years to 5 years: 1/2 tablet orally every 12 hours as needed.
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years and older: 1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 9 mg-12 mg/5 mL oral suspension, extended release:
2 years to 5 years: 2.5 mL orally every 12 hours, not to exceed 5 mL in 24 hours.
6 years to 11 years: 5 mL orally every 12 hours, not to exceed 10 mL in 24 hours.
12 years or older: 5 to 10 mL orally every 12 hours, not to exceed 20 mL in 24 hours.

phenylephrine-pyrilamine 10 mg-25 mg oral tablet:
6 years to 11 years: 1/2 tablet orally every 4 to 6 hours, not to exceed 3 tablets in 24 hours.
12 years or older: 1 tablet orally every 4 to 6 hours, not to exceed 6 tablets in 24 hours.

phenylephrine-pyrilamine 10 mg-30 mg/5 mL oral liquid:
6 years to 11 years: 2.5 mL orally every 6 to 8 hours as needed, not to exceed 25 mL in 24 hours.
12 years or older: 5 mL orally every 6 to 8 hours as needed, not to exceed 15 mL in 24 hours.

Usual Pediatric Dose for Cold Symptoms

phenylephrine-pyrilamine 5 mg-16 mg/5 mL oral suspension, extended release:
phenylephrine-pyrilamine 12.5 mg-30 mg/5 mL oral suspension:
2 years to 5 years: 2.5 mL orally every 12 hours as needed.
6 years to 11 years: 5 mL orally every 12 hours as needed.
12 years or older: 5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 12.5 mg-30 mg oral tablet, chewable:
2 years to 5 years: 1/2 tablet orally every 12 hours as needed.
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years or older: 1 to 2 tablet orally every 12 hours as needed.

phenylephrine-pyrilamine 5 mg-30 mg/5 mL oral suspension:
2 years to 5 years: 2.5 to 5 mL orally every 12 hours as needed.
6 years or older: 5 to 10 mL orally every 12 hours as needed.

phenylephrine-pyrilamine 25 mg-60 mg oral tablet:
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years or older: 1 to 2 tablet orally every 12 hours as needed.

phenylephrine-pyrilamine 10 mg-16 mg oral tablet, chewable, extended release:
2 years to 5 years: 1/2 tablet orally every 12 hours as needed.
6 years to 11 years: 1/2 to 1 tablet orally every 12 hours as needed.
12 years and older: 1 or 2 tablets orally every 12 hours as needed.

phenylephrine-pyrilamine 9 mg-12 mg/5 mL oral suspension, extended release:
2 years to 5 years: 2.5 mL orally every 12 hours, not to exceed 5 mL in 24 hours.
6 years to 11 years: 5 mL orally every 12 hours, not to exceed 10 mL in 24 hours.
12 years or older: 5 to 10 mL orally every 12 hours, not to exceed 20 mL in 24 hours.

phenylephrine-pyrilamine 10 mg-25 mg oral tablet:
6 years to 11 years: 1/2 tablet orally every 4 to 6 hours, not to exceed 3 tablets in 24 hours.
12 years or older: 1 tablet orally every 4 to 6 hours, not to exceed 6 tablets in 24 hours.

phenylephrine-pyrilamine 10 mg-30 mg/5 mL oral liquid:
6 years to 11 years: 2.5 mL orally every 6 to 8 hours as needed, not to exceed 25 mL in 24 hours.
12 years or older: 5 mL orally every 6 to 8 hours as needed, not to exceed 15 mL in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Use with caution in patients with hypertension, cardiovascular disease, hyperthyroidism, diabetes, narrow angle glaucoma or prostatic hypertrophy.

Dialysis

Data not available

See also...