Neomycin Dosage
This dosage information may not include all the information needed to use Neomycin safely and effectively. See additional information for Neomycin.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Bowel Preparation
1 g orally every hour for 4 doses followed by 1 g every 4 hours for 5 doses
Alternate dosing: 6 g/day orally divided every 4 hours for 2 to 3 days
Usual Adult Dose for Hepatic Encephalopathy
4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days
Usual Adult Dose for Hepatic Coma
4 to 12 g/day orally divided every 4 to 6 hours for 5 to 6 days
Usual Adult Dose for Diarrhea
3 g/day orally in 4 divided doses
Usual Pediatric Dose for Bowel Preparation
The safety and efficacy of neomycin in children less than 18 years of age has not been established. However, the use of neomycin may be appropriate is some situations.
Less than 1 month: 50 mg/kg/day orally divided every 6 hours
1 year to 18 years: 50 to 100 mg/kg/day orally divided every 6 hours
Usual Pediatric Dose for Hepatic Encephalopathy
The safety and efficacy of neomycin in children less than 18 years of age has not been established. However, the use of neomycin may be appropriate is some situations.
1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days
Usual Pediatric Dose for Hepatic Coma
The safety and efficacy of neomycin in children less than 18 years of age has not been established. However, the use of neomycin may be appropriate is some situations.
1 month to 18 years: 50 to 100 mg/kg/day orally divided every 6 to 8 hours for 5 to 6 days
Usual Pediatric Dose for Diarrhea
The safety and efficacy of neomycin in children less than 18 years of age has not been established. However, the use of neomycin may be appropriate is some situations.
Less than 1 month: 50 mg/kg/day orally divided every 6 hours
1 year to 18 years: 50 mg/kg/day orally divided every 6 hours for 2 to 3 days
Renal Dose Adjustments
Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral neomycin. Use of a less nephrotoxic medication may be a consideration for this patient.
Liver Dose Adjustments
In chronic hepatic insufficiency, it may be necessary to give neomycin sulfate 4 g daily for an indefinite period, if less toxic drugs cannot be used.
Dose Adjustments
Caution should be used when administering neomycin to patients with renal impairment. Dose reduction should be considered in these patients.
Precautions
To minimize the risk of toxicity use the lowest possible dose and the shortest possible treatment period to control the condition. Treatment periods of longer than 2 weeks are not recommended.
Do not use in patients with intestinal obstruction.
Do not use in patients with inflammatory or ulcerative gastrointestinal disease due to the potential for increased gastrointestinal absorption of the drug.
Patients should be monitored for nephrotoxicity and ototoxicity.
Neomycin should be used with caution in patients with hearing impairment, renal impairment or neuromuscular disorders.
Dialysis
Patients with impaired renal function have a high risk of developing nephrotoxicity and ototoxicity with oral neomycin. Use of a less nephrotoxic medication may be a consideration for this patient.
