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Meclofenamate Dosage
This dosage information may not include all the information needed to use Meclofenamate safely and effectively. See additional information for Meclofenamate.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Pain
Mild to moderate pain:
Initial dose: 50 mg orally every 4 to 6 hours
Maintenance dose: 50 mg orally every 4 to 6 hours or 100 mg orally every 6 hours
Maximum dose: 400 mg orally per day
Usual Adult Dose for Dysmenorrhea
Primary dysmenorrhea and excessive menstrual blood loss:
100 mg orally 3 times a day, for up to 6 days, starting at the onset of menstrual flow
Maximum dose: 400 mg orally per day
Usual Adult Dose for Osteoarthritis
200 to 400 mg orally per day, administered in 3 to 4 equal doses
Maximum dose: 400 mg orally per day
Usual Adult Dose for Rheumatoid Arthritis
200 to 400 mg orally per day, administered in 3 to 4 equal doses
Maximum dose: 400 mg orally per day
Renal Dose Adjustments
The manufacturer recommends a lower daily dose in patients with significant renal dysfunction to avoid drug accumulation.
Liver Dose Adjustments
No adjustment recommended
Dose Adjustments
After a satisfactory response has been achieved, the dosage should be adjusted as required. A lower dosage may suffice for long-term administration.
A lower starting dose and careful follow-up is recommended in elderly patients due to adverse effects that are more common in this population.
Precautions
If gastrointestinal upset occurs, meclofenamate may be administered with meals or milk.
Safety and effectiveness have not been established in pediatric patients below the age of 14 years.
Dialysis
No adjustment recommended
Other Comments
Although improvement may be seen in some patients in a few days, 2 to 3 weeks of treatment may be required to obtain the optimum therapeutic benefit.
