Levonorgestrel Dosage

Usual Adult Dose for Contraception

Contraception:
Mirena: One 52 mg intrauterine system inserted within seven days of the onset of menstruation or immediately after first-trimester abortion. One system is effective for 5 years.

Skyla: One 13.5 mg intrauterine system inserted during seven days of the menstrual cycle or immediately after a first trimester abortion. Postpone postpartum insertion and insertions following second trimester abortions a minimum of six weeks or until the uterus is fully involuted. One system is effective for 3 years.

Comments:
Back up contraception not needed when Skyla is inserted as directed.
Mirena is also indicated for the treatment of heavy menstrual bleeding in women who choose to use intrauterine contraception as their method of contraception.

Emergency contraception after unprotected intercourse or after contraceptive failure:
one 0.75 mg tablet orally within 72 hours of unprotected intercourse followed by 0.75 mg orally 12 hours after the first dose.
or
one 1.5 mg tablet orally as soon as possible within 72 hours of unprotected intercourse.

Comment: Efficacy is better if the tablet(s) is taken as soon as possible after unprotected intercourse.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

This product is not intended for use in premenarcheal populations.

Dialysis

Data not available

Other Comments

General: Mirena is recommended for women who have had at least one child. Skyla can be used whether or not you have had a child.

Patient advice: Patients should be counseled that this product does not protect against HIV infection (AIDS) and other sexually transmitted diseases.

See also...