Hyosyne Dosage

Generic name: hyoscyamine sulfate
Dosage form: oral solution

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This dosage information does not include all the information needed to use Hyosyne safely and effectively. See full prescribing information for Hyosyne.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

HYOSYNE ORAL DROPS
(Hyoscyamine Sulfate Oral Solution)

Dosage may be adjusted according to the conditions and severity of symptoms. Measuredosage very carefully.
Adults and pediatric patients 12 years of age and older: 1 to 2 mL every four hours or as needed. Do not exceed 12 mL in 24 hours.
Pediatric patients 2 to under 12 years of age: 1/4 to 1 mL every four hours or as needed. Do not exceed 6 mL in 24 hours.
Pediatric patients under 2 years of age: The following dosage guide is based upon body weight. The doses may be repeated every four hours or as needed.

Body Weight Usual Dose Do Not Exceed


In 24 Hours
3.4 kg (7.5 lb.)
4 drops
24 drops
5 kg (11 lb.)
5 drops
30 drops
7 kg (15 lb.)
6 drops
36 drops
10 kg (22 lb.)
8 drops
48 drops

Package of Hyoscyamine Sulfate Oral Drops is accompanied with a dropper having markings of 3, 4, 5 DROPS, and 0.25 mL. The approximate equivalent amount of hyoscyamine sulfate drops (mL) and its equivalent amount of hyoscyamine sulfate (mg) for each marking are as follows:







Approximate Equivalent Amount

Marking on Dropper Hyoscyamine Sulfate Oral Drops Solution (mL)

Hyoscyamine Sulfate (mg)
3 DROPS
0.08 mL

0.01 mg
4 DROPS
0.11 mL

0.01375 mg
5 DROPS
0.14 mL

0.0175 mg
0.25 mL
0.25 mL

0.03125 mg

HYOSYNE ELIXIR
(Hyoscyamine Sulfate Elixir)
Dosage may be adjusted according to the conditions and severity of symptoms. Measure dosage very carefully.
Adults and pediatric patients 12 years of age and older: 1 to 2 teaspoonfuls every four hours or as needed. Do not exceed 12 teaspoonfuls in 24 hours.
Pediatric patients 2 to under 12 years of age: Please see the following dosage guide is based on body weight. The doses may be repeated every four hours or as needed. Do not exceed 6teaspoonfuls in 24 hours.

Body Weight
Usual Dose
10 kg (22 lb.)
1/4 teaspoon (1.25 mL)
20 kg (44 lb.)
1/2 teaspoonful (2.5 mL)
40 kg (88 lb.)
3/4 teaspoonful (3.75 mL)
50 kg (110 lb.)
1 teaspoonful (5 mL)
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