GlucaGen Dosage

Generic name: glucagon hydrochloride
Dosage form: hypokit

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

For GlucaGenHypoKit:

Treatment of severe hypoglycemia

1.
Using the supplied prefilled syringe, carefully insert the needle through the rubber stopper of the vial containing GlucaGen powder and inject all the liquid from the syringe into the vial.
2.
Shake the vial gently until the powder is completely dissolved and no particles remain in the fluid. The reconstituted fluid should be clear and of water-like consistency.
3.
The reconstituted GlucaGen gives a concentration of approximately 1 mg/mL glucagon.
4.
The reconstituted GlucaGen should be used immediately after reconstitution.
5.
Inject 1 mL (adults and children, weighing more than 55 lbs (25 kg)) or 0.5 mL (children weighing less than 55 lbs (25 kg)) subcutaneously, intramuscularly, or intravenously. If the weight is not known: children younger than 6 years should be given a 0.5 mL and children 6 years and older should be given 1 mL.
6.
Discard any unused portion.
7.
Emergency assistance should be sought immediately after subcutaneous or intramuscular injection of glucagon.
8.
The glucagon injection may be repeated using a new kit while waiting for emergency assistance.
9.
Intravenous glucose MUST be administered if the patient fails to respond to glucagon.
10.
When the patient has responded to the treatment, give oral carbohydrates to restore the liver glycogen and prevent recurrence of hypoglycemia.

For GlucaGen Diagnostic Kit and the GlucaGen 10-pack:

Use as a diagnostic aid

1.
GlucaGen should be reconstituted with 1 mL of Sterile Water for Reconstitution (if supplied) or 1 mL of Sterile Water for Injection, USP. Using a syringe, withdraw all of the Sterile Water for Reconstitution (if supplied) or 1 mL Sterile Water for Injection, USP and inject into the GlucaGen vial.
2.
Shake the vial gently until the powder is completely dissolved and no particles remain in the fluid. The reconstituted fluid should be clear and of water-like consistency.
3.
The reconstituted GlucaGen gives a concentration of approximately 1 mg/mL glucagon.
4.
The reconstituted GlucaGen should be used immediately after reconstitution.
5.
GlucaGen must be administered by medical personnel.
6.
Discard any unused portion.
7.
Onset of action after an injection will depend on the organ under examination and route of administration [see Pharmacodynamics (12.2)].
8.
The usual diagnostic dose for relaxation of the stomach, duodenal bulb, duodenum, and small bowel is 0.2 mg to 0.5 mg given intravenously or 1 mg given intramuscularly; the usual dose to relax the colon is 0.5 mg to 0.75 mg intravenously and 1 mg to 2 mg intramuscularly [see Pharmacodynamics (12.2)].
9.
After the end of the diagnostic procedure, give oral carbohydrates to patients who have been fasting, if this is compatible with the diagnostic procedure applied.

The GlucaGen Diagnostic Kit and the GlucaGen 10-pack presentations are intended only for use by healthcare providers as a diagnostic aid. The GlucaGen Diagnostic Kit and the GlucaGen 10-pack presentations are not intended for use by patients to treat severe hypoglycemia because they are not packaged with a syringe and diluent necessary for rapid preparation and administration during an emergency outside of a healthcare facility.

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