Gentamicin / Prednisolone Ophthalmic Dosage

Medically reviewed by Drugs.com. Last updated on Aug 4, 2023.

Usual Adult Dose for Uveitis

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Usual Adult Dose for Ocular Infection

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Usual Adult Dose for Bacterial Conjunctivitis

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Usual Adult Dose for Keratitis

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Usual Adult Dose for Keratoconjunctivitis

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Usual Adult Dose for Blepharitis

Ointment: Apply a small amount (1/2 inch ribbon) to conjunctival sac of affected eye(s) 1 to 3 times a day

Suspension: Instill 1 drop into the conjunctival sac of the affected eye(s) 2 to 4 times a day; during the initial 24 to 48 hours, may increase frequency up to 1 drop every hour if necessary

Comments:

• A maximum of 20 mL of suspension or a maximum of 8 g of ointment should be prescribed initially and should not be refilled without further evaluation of the patient's condition.
• If signs/symptoms fail to improve after 2 days of treatment, the patient should be re-evaluated.
• Care should be taken as to not discontinue therapy prematurely.

Uses: For the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or risk of bacterial ocular infection exists; the anti-infective component of this drug is active against the following common bacterial eye pathogens: Staphylococcus aureaus, Streptococcus pyogenes, S pneumoniae, Enterobacter aerogenes, Escherichia coli, Haemophilus influenzae, Klebsiella pneumoniae, Neisseria gonorrhoeae, Pseudomonas aeruginosa, and Serratia marcescens

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• For topical ophthalmic use only; this drug should never be injected subconjunctivally nor introduced into the anterior chamber of the eye.
• Suspension: Shake well before use

Storage requirements:

• Suspension: Protect from freezing and from heat of 104F (40C) and above.

Monitoring:

• Ocular: Routinely measure intraocular pressure if this drug is used for 10 days or longer.

Patient advice:

• Avoid touching the tip of the tube/bottle to eyelids or any other surface; use by more than 1 person may spread infection.
• Discontinue use and consult a physician if inflammation or pain persists longer than 48 hours or becomes aggravated.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer