Gadoxetate Disodium Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Liver Magnetic Resonance Imaging

0.1 mL/kg body weight(0.025 mmol/kg body weight) administered undiluted as a single intravenous bolus injection at a flow rate of approximately 2 mL/second.

Renal Dose Adjustments

Gadolinium based contrast agents increase the risk for nephrogenic systemic fibrosis (NSF) in patients with acute or chronic severe renal insufficiency (glomerular filtration rate less than 30 mL/min/1.73 m2), or acute renal insufficiency of any severity due to the hepatorenal syndrome or in the perioperative liver transplantation period. In these patients, avoid use of gadolinium based contrast agents unless the diagnostic information is essential and not available with noncontractile enhanced magnetic resonance imaging (MRI).

Liver Dose Adjustments

A dose adjustment is not necessary for patients with hepatic impairment.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

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