Skip to main content

Fosinopril / Hydrochlorothiazide Dosage

Medically reviewed by Drugs.com. Last updated on Aug 11, 2023.

Applies to the following strengths: 10 mg-12.5 mg; 20 mg-12.5 mg

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Fosinopril 10 to 40 mg-Hydrochlorothiazide 12.5 to 37.5 mg orally per day

Comments: The effect of fosinopril 10 mg-hydrochlorothiazide 12.5 mg was similar to the effect seen with monotherapy using either fosinopril 40 mg or hydrochlorothiazide 37.5 mg.

Use: Treatment of hypertension when the desired effect has not been achieved with monotherapy or as substitution for the titrated individual components.

Renal Dose Adjustments

Mild to moderate renal dysfunction (CrCl 30 mL/min/1.73 m2 or greater): No adjustment recommended
Severe renal dysfunction (CrCl less than 30 mL/min/1.73 m2, serum creatinine roughly greater than or equal to 3 mg/dL or 265 mcmol/L): Not recommended

Liver Dose Adjustments

Use with caution

Precautions

US BOXED WARNING:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Monitoring:


Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.