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Filgrastim Dosage

Medically reviewed by Drugs.com. Last updated on Jun 16, 2023.

Applies to the following strengths: aafi 300 mcg/0.5 mL; aafi 480 mcg/0.8 mL; aafi 300 mcg/mL; aafi 480 mcg/1.6 mL; 300 mcg/mL; 300 mcg/0.5 mL; 480 mcg/0.8 mL; 480 mcg/1.6 mL; sndz 300 mcg/0.5 mL; sndz 480 mcg/0.8 mL; ayow 300 mcg/0.5 mL; ayow 300 mcg/mL; ayow 480 mcg/0.8 mL; ayow 480 mcg/1.6 mL

Usual Adult Dose for Neutropenia Associated with Chemotherapy

Initial dose: 5 mcg/kg ONCE a day via subcutaneous injection, short IV infusion (over 15 to 30 minutes) OR continuous IV infusion
Titration dose: Doses may be escalated in 5 mcg/kg doses in each chemotherapy cycle
Duration of therapy: Up to 2 weeks OR until the absolute neutrophil count (ANC) nadir reaches 10,000/mm3

Comments:


Uses:

Usual Adult Dose for Bone Marrow Transplantation

Following Bone Marrow Transplantation (BMT):


Neutrophil Recovery Following BMT:

Comments:

Uses:

Usual Adult Dose for Peripheral Progenitor Cell Transplantation

10 mcg/kg via subcutaneous injection once a day

Comments:


Uses:

Usual Adult Dose for Neutropenia

Congenital Neutropenia:


Cyclic/Idiopathic Neutropenia:

Comments:

Uses:

Usual Adult Dose for Neutropenia Associated with Radiation

10 mcg/kg via subcutaneous injection once a day

Comments:


Uses:

Usual Pediatric Dose for Neutropenia Associated with Chemotherapy

Initial dose: 5 mcg/kg ONCE a day via subcutaneous injection, short IV infusion (over 15 to 30 minutes) OR continuous IV infusion
Titration dose: Doses may be escalated in 5 mcg/kg doses in each chemotherapy cycle
Duration of therapy: Up to 2 weeks OR until the ANC nadir reaches 10,000/mm3

Comments:


Uses:

Usual Pediatric Dose for Bone Marrow Transplantation

Following BMT:


Neutrophil Recovery Following BMT:

Comments:

Uses:

Usual Pediatric Dose for Peripheral Progenitor Cell Transplantation

10 mcg/kg via subcutaneous injection once a day

Comments:


Uses:

Usual Pediatric Dose for Neutropenia

Congenital Neutropenia:


Cyclic/Idiopathic Neutropenia:

Comments:

Uses:

Usual Pediatric Dose for Neutropenia Associated with Radiation

10 mcg/kg via subcutaneous injection once a day

Comments:


Uses:

Renal Dose Adjustments

No adjustment recommended.

Liver Dose Adjustments

No adjustment recommended.

Dose Adjustments

Therapeutic drug monitoring/range: ANC greater than 10,0000/mm3: Treatment should be stopped.

Precautions

CONTRAINDICATIONS:


Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:


Storage requirements: Store refrigerated at 2C to 8C and do not freeze; protect from light.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

IV compatibility:

General:

Monitoring:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.