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Fenofibrate Dosage

Medically reviewed by Drugs.com. Last updated on Aug 11, 2023.

Applies to the following strengths: 48 mg; 145 mg; 54 mg; 160 mg; 67 mg; micronized 200 mg; 134 mg; 40 mg; 120 mg; 43 mg; 130 mg; 30 mg; 90 mg; 50 mg; 150 mg

Usual Adult Dose for Hyperlipidemia

Multiple products available:

1 capsule or tablet orally once a day (range: 90 to 200 mg per dose unit)


Some examples of branded tablets and capsules; multiple generics available:

Comments:

Uses: As an adjunct therapy to diet for the treatment of primary hypercholesterolemia and mixed dyslipidemia.

Usual Adult Dose for Hyperlipoproteinemia Type IIa (Elevated LDL)

Multiple products available:

1 capsule or tablet orally once a day (range: 90 to 200 mg per dose unit)


Some examples of branded tablets and capsules; multiple generics available:

Comments:

Uses: As an adjunct therapy to diet for the treatment of primary hypercholesterolemia and mixed dyslipidemia.

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL)

Multiple products available:

1 capsule or tablet orally once a day (range: 90 to 200 mg per dose unit)


Some examples of branded tablets and capsules; multiple generics available:

Comments:

Uses: As an adjunct therapy to diet for the treatment of primary hypercholesterolemia and mixed dyslipidemia.

Usual Adult Dose for Dyslipidemia

Multiple products available:

1 capsule or tablet orally once a day (range: 90 to 200 mg per dose unit)


Some examples of branded tablets and capsules; multiple generics available:

Comments:

Uses: As an adjunct therapy to diet for the treatment of primary hypercholesterolemia and mixed dyslipidemia.

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL)

Dosing is product specific; available as micronized capsules, capsules, and tablets:

MICRONIZED CAPSULES:

CAPSULES:
TABLETS:

TITRATION: Individualize dose according to response and adjust as necessary following repeat lipid determinations at 4 to 8 week intervals; if lipid levels fall significantly, dose reduction should be considered.

Comments:

Use: As an adjunct to diet for the treatment of severe hypertriglyceridemia.

Usual Adult Dose for Hyperlipoproteinemia Type V (Elevated Chylomicrons + VLDL)

Dosing is product specific; available as micronized capsules, capsules, and tablets:

MICRONIZED CAPSULES:

CAPSULES:
TABLETS:

TITRATION: Individualize dose according to response and adjust as necessary following repeat lipid determinations at 4 to 8 week intervals; if lipid levels fall significantly, dose reduction should be considered.

Comments:

Use: As an adjunct to diet for the treatment of severe hypertriglyceridemia.

Usual Adult Dose for Hypertriglyceridemia

Dosing is product specific; available as micronized capsules, capsules, and tablets:

MICRONIZED CAPSULES:

CAPSULES:
TABLETS:

TITRATION: Individualize dose according to response and adjust as necessary following repeat lipid determinations at 4 to 8 week intervals; if lipid levels fall significantly, dose reduction should be considered.

Comments:

Use: As an adjunct to diet for the treatment of severe hypertriglyceridemia.

Renal Dose Adjustments

Mild to moderate renal dysfunction: Initiate at lower doses and increase only after evaluating the effects of therapy on renal function and lipid levels:


Severe renal impairment: Contraindicated

Liver Dose Adjustments

Active liver disease: Contraindicated

Dose Adjustments

Elderly: Due to the higher incidence of renal impairment in this patient population, dose selection should be based on renal function; monitor renal function during therapy

Precautions

CONTRAINDICATIONS:


Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.

Dialysis

Contraindicated

Other Comments

Administration advice:


Concomitant use with bile acid binding resin:

Storage requirements:

General:

Monitoring:

Patient advice:

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.