Enalapril / Hydrochlorothiazide Dosage

This dosage information may not include all the information needed to use Enalapril / Hydrochlorothiazide safely and effectively. See additional information for Enalapril / Hydrochlorothiazide.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Congestive Heart Failure

Initial dose: 1 tablet of (enalapril-hydrochlorothiazide 5 mg/12.5 mg) once a day. Determine dosage by individual titration.
Maintenance dose: May increase up to a maximum dose of 2 tablets of (enalapril-hydrochlorothiazide 10 mg/25 mg) in 1-2 divided doses a day.

Usual Adult Dose for Hypertension

Initial dose: 1 tablet of (enalapril-hydrochlorothiazide 5 mg/12.5 mg) once a day. Determine dosage by individual titration.
Maintenance dose: May increase up to a maximum dose of 2 tablets of (enalapril-hydrochlorothiazide 10 mg/25 mg) in 1-2 divided doses a day.

Renal Dose Adjustments

The usual regimens of therapy with enalapril-hydrochlorothiazide need not be adjusted as long as the patient's creatinine clearance is >30 mL/min. In patients with more severe renal impairment, loop diuretics are preferred to thiazides, so enalapril-hydrochlorothiazide is not recommended.

Liver Dose Adjustments

Thiazide diuretics should be used with caution in patients with hepatic impairment.

Dose Adjustments

The hydrochlorothiazide dose should generally not be increased until 2-3 weeks have elapsed.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Enalapril is moderately dialyzable (20%-50%).

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