Drospirenone / Estradiol Dosage

This dosage information may not include all the information needed to use Drospirenone / Estradiol safely and effectively. See additional information for Drospirenone / Estradiol.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Postmenopausal Symptoms

Treatment of moderate to severe vasomotor symptoms:

drospirenone 0.25 mg/estradiol 0.5 mg tablet or drospirenone 0.5 mg/estradiol 1 mg tablet, 1 tablet orally each day.

Treatment of moderate to severe symptoms of vulvar and vaginal atrophy:

drospirenone 0.5 mg/estradiol 1 mg tablet, 1 tablet orally each day.

Renal Dose Adjustments

The medication is contraindicated in patients with renal insufficiency.

Liver Dose Adjustments

The medication is contraindicated in patients with hepatic dysfunction.

Precautions

Use of estrogen should be limited to the lowest effective dose available and for the shortest duration consistent with treatment goals taking into account risks for the individual woman. Patients should be reevaluated periodically as clinically appropriate to determine if treatment is still necessary.

Dialysis

The medication is contraindicated in patients with renal insufficiency.

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