Dopamine Dosage
This dosage information may not include all the information needed to use Dopamine safely and effectively. See additional information for Dopamine.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Nonobstructive Oliguria
Initial dose: 1 to 5 mcg/kg/min by continuous IV infusion.
Titrate to desired response. Administration at rates greater than 50 mcg per kg per minute have been used safely in serious situations.
Usual Adult Dose for Shock
Initial dose: 1 to 5 mcg/kg/min by continuous IV infusion.
Titrate to desired response. Administration at rates greater than 50 mcg per kg per minute have been used safely in serious situations.
Usual Pediatric Dose for Nonobstructive Oliguria
less than 1 month: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response.
1 month or older: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response. Maximum of 50 mcg/kg/min.
The hemodynamic effects of dopamine are dose dependent:
Low dosage: 1 to 5 mcg/kg/minute, increased renal blood flow and urine output
Intermediate dosage: 5 to 15 mcg/kg/minute, increased renal blood flow, heart rate, cardiac contractility, cardiac output, and blood pressure
High dosage: greater than 15 mcg/kg/minute, alpha-adrenergic effects begin to predominate, vasoconstriction, increased blood pressure
Usual Pediatric Dose for Shock
less than 1 month: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response.
1 month or older: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response. Maximum of 50 mcg/kg/min.
The hemodynamic effects of dopamine are dose dependent:
Low dosage: 1 to 5 mcg/kg/minute, increased renal blood flow and urine output
Intermediate dosage: 5 to 15 mcg/kg/minute, increased renal blood flow, heart rate, cardiac contractility, cardiac output, and blood pressure
High dosage: greater than 15 mcg/kg/minute, alpha-adrenergic effects begin to predominate, vasoconstriction, increased blood pressure
Renal Dose Adjustments
Low-dose dopamine (1 to 5 mcg/kg/minute) is typically used to increase renal blood flow and urine output.
Liver Dose Adjustments
Data not available
Dose Adjustments
Increase gradually in 5 to 10 mcg/kg/min increments up to a rate of 20 to 50 mcg/kg/min, as needed.
Dialysis
Data not available
Other Comments
Administration of rates > 50 mcg/kg/min have been used safely in advanced circulatory decompensation states.
