Dopamine Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Nonobstructive Oliguria

Initial dose: 1 to 5 mcg/kg/min by continuous IV infusion.
Titrate to desired response. Administration at rates greater than 50 mcg per kg per minute have been used safely in serious situations.

Usual Adult Dose for Shock

Initial dose: 1 to 5 mcg/kg/min by continuous IV infusion.
Titrate to desired response. Administration at rates greater than 50 mcg per kg per minute have been used safely in serious situations.

Usual Pediatric Dose for Nonobstructive Oliguria

less than 1 month: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response.

1 month or older: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response. Maximum of 50 mcg/kg/min.

The hemodynamic effects of dopamine are dose dependent:
Low dosage: 1 to 5 mcg/kg/minute, increased renal blood flow and urine output
Intermediate dosage: 5 to 15 mcg/kg/minute, increased renal blood flow, heart rate, cardiac contractility, cardiac output, and blood pressure
High dosage: greater than 15 mcg/kg/minute, alpha-adrenergic effects begin to predominate, vasoconstriction, increased blood pressure

Usual Pediatric Dose for Shock

less than 1 month: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response.

1 month or older: 1 to 20 mcg/kg/min by continuous IV infusion, titrated to desired response. Maximum of 50 mcg/kg/min.

The hemodynamic effects of dopamine are dose dependent:
Low dosage: 1 to 5 mcg/kg/minute, increased renal blood flow and urine output
Intermediate dosage: 5 to 15 mcg/kg/minute, increased renal blood flow, heart rate, cardiac contractility, cardiac output, and blood pressure
High dosage: greater than 15 mcg/kg/minute, alpha-adrenergic effects begin to predominate, vasoconstriction, increased blood pressure

Renal Dose Adjustments

Low-dose dopamine (1 to 5 mcg/kg/minute) is typically used to increase renal blood flow and urine output.

Liver Dose Adjustments

Data not available

Dose Adjustments

Increase gradually in 5 to 10 mcg/kg/min increments up to a rate of 20 to 50 mcg/kg/min, as needed.

Dialysis

Data not available

Other Comments

Administration of rates > 50 mcg/kg/min have been used safely in advanced circulatory decompensation states.

Hide
(web3)