Dobutamine Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Congestive Heart Failure

The rate of infusion needed to increase cardiac output usually ranges from 2.5 to 15 mcg/kg/min. The initial dosage may be titrated upward by 2.5 mcg per kg per minute as tolerated to maintain systemic blood pressure and urine output. Administration rates greater than 40 mcg per kg per min may be necessary in serious situations.

Usual Adult Dose for Shock

The rate of infusion needed to increase cardiac output usually ranges from 2.5 to 15 mcg/kg/min. The initial dosage may be titrated upward by 2.5 mcg per kg per minute as tolerated to maintain systemic blood pressure and urine output. Administration rates greater than 40 mcg per kg per min may be necessary in serious situations.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

The rate of administration and the duration of therapy should be adjusted according to the patient's response as determined by heart rate, presence of ectopic activity, blood pressure, urine flow, and, whenever possible, measurement of central venous or pulmonary wedge pressure and cardiac output.

Dialysis

Data not available

Other Comments

On rare occasions, infusion rates up to 40 mcg/kg/min have been required to obtain the desired effect.
Concentrations up to 5,000 mcg/mL have been administered (250 mg/ 50 mL). The final volume administered should be determined by the fluid requirements of the patient.

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