Diphtheria Toxoid / Hepatitis B Pediatric Vaccine / Pertussis, Acellular / Poliovirus Vaccine, Inactivated / Tetanus Toxoid Dosage

Usual Pediatric Dose for Poliomyelitis Prophylaxis

Active immunization against diphtheria, tetanus, pertussis (whooping cough), all known subtypes of hepatitis B virus, and poliomyelitis caused by poliovirus Types 1, 2, and 3:
6 months to 5 years:
3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks). The customary age for the first dose is 2 months of age, but it may be given starting at 6 weeks of age. The preferred administration site is the anterolateral aspect of the thigh for children younger than 1 year. In older children, the deltoid muscle is usually large enough for an intramuscular injection. The vaccine should not be injected in the gluteal area or areas where there may be a major nerve trunk. Gluteal injections may result in suboptimal hepatitis B immune response.

Modified Schedules:
Children Previously Vaccinated With One or More Doses of Hepatitis B Vaccine: Infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth may be administered 3 doses of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) according to the recommended schedule.

Children Previously Vaccinated With One or More Doses of INFANRIX (diphtheria/tetanus/pertussis,acel): diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the DTaP series in infants who have received 1 or 2 doses of INFANRIX and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Children Previously Vaccinated With One or More Doses of Poliovirus vaccine, inactivated (IPV):
diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the IPV series in infants who have received 1 or 2 doses of IPV and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Usual Pediatric Dose for Diphtheria Prophylaxis

Active immunization against diphtheria, tetanus, pertussis (whooping cough), all known subtypes of hepatitis B virus, and poliomyelitis caused by poliovirus Types 1, 2, and 3:
6 months to 5 years:
3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks). The customary age for the first dose is 2 months of age, but it may be given starting at 6 weeks of age. The preferred administration site is the anterolateral aspect of the thigh for children younger than 1 year. In older children, the deltoid muscle is usually large enough for an intramuscular injection. The vaccine should not be injected in the gluteal area or areas where there may be a major nerve trunk. Gluteal injections may result in suboptimal hepatitis B immune response.

Modified Schedules:
Children Previously Vaccinated With One or More Doses of Hepatitis B Vaccine: Infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth may be administered 3 doses of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) according to the recommended schedule.

Children Previously Vaccinated With One or More Doses of INFANRIX (diphtheria/tetanus/pertussis,acel): diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the DTaP series in infants who have received 1 or 2 doses of INFANRIX and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Children Previously Vaccinated With One or More Doses of Poliovirus vaccine, inactivated (IPV):
diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the IPV series in infants who have received 1 or 2 doses of IPV and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Usual Pediatric Dose for Pertussis Prophylaxis

Active immunization against diphtheria, tetanus, pertussis (whooping cough), all known subtypes of hepatitis B virus, and poliomyelitis caused by poliovirus Types 1, 2, and 3:
6 months to 5 years:
3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks). The customary age for the first dose is 2 months of age, but it may be given starting at 6 weeks of age. The preferred administration site is the anterolateral aspect of the thigh for children younger than 1 year. In older children, the deltoid muscle is usually large enough for an intramuscular injection. The vaccine should not be injected in the gluteal area or areas where there may be a major nerve trunk. Gluteal injections may result in suboptimal hepatitis B immune response.

Modified Schedules:
Children Previously Vaccinated With One or More Doses of Hepatitis B Vaccine: Infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth may be administered 3 doses of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) according to the recommended schedule.

Children Previously Vaccinated With One or More Doses of INFANRIX (diphtheria/tetanus/pertussis,acel): diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the DTaP series in infants who have received 1 or 2 doses of INFANRIX and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Children Previously Vaccinated With One or More Doses of Poliovirus vaccine, inactivated (IPV):
diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the IPV series in infants who have received 1 or 2 doses of IPV and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Usual Pediatric Dose for Tetanus Prophylaxis

Active immunization against diphtheria, tetanus, pertussis (whooping cough), all known subtypes of hepatitis B virus, and poliomyelitis caused by poliovirus Types 1, 2, and 3:
6 months to 5 years:
3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks). The customary age for the first dose is 2 months of age, but it may be given starting at 6 weeks of age. The preferred administration site is the anterolateral aspect of the thigh for children younger than 1 year. In older children, the deltoid muscle is usually large enough for an intramuscular injection. The vaccine should not be injected in the gluteal area or areas where there may be a major nerve trunk. Gluteal injections may result in suboptimal hepatitis B immune response.

Modified Schedules:
Children Previously Vaccinated With One or More Doses of Hepatitis B Vaccine: Infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth may be administered 3 doses of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) according to the recommended schedule.

Children Previously Vaccinated With One or More Doses of INFANRIX (diphtheria/tetanus/pertussis,acel): diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the DTaP series in infants who have received 1 or 2 doses of INFANRIX and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Children Previously Vaccinated With One or More Doses of Poliovirus vaccine, inactivated (IPV):
diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the IPV series in infants who have received 1 or 2 doses of IPV and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Usual Pediatric Dose for Hepatitis B Prophylaxis

Active immunization against diphtheria, tetanus, pertussis (whooping cough), all known subtypes of hepatitis B virus, and poliomyelitis caused by poliovirus Types 1, 2, and 3:
6 months to 5 years:
3 doses of 0.5 mL, given intramuscularly, at 6- to 8-week intervals (preferably 8 weeks). The customary age for the first dose is 2 months of age, but it may be given starting at 6 weeks of age. The preferred administration site is the anterolateral aspect of the thigh for children younger than 1 year. In older children, the deltoid muscle is usually large enough for an intramuscular injection. The vaccine should not be injected in the gluteal area or areas where there may be a major nerve trunk. Gluteal injections may result in suboptimal hepatitis B immune response.

Modified Schedules:
Children Previously Vaccinated With One or More Doses of Hepatitis B Vaccine: Infants born of HBsAg-negative mothers and who received a dose of hepatitis B vaccine at or shortly after birth may be administered 3 doses of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) according to the recommended schedule.

Children Previously Vaccinated With One or More Doses of INFANRIX (diphtheria/tetanus/pertussis,acel): diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the DTaP series in infants who have received 1 or 2 doses of INFANRIX and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Children Previously Vaccinated With One or More Doses of Poliovirus vaccine, inactivated (IPV):
diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX) may be used to complete the first 3 doses of the IPV series in infants who have received 1 or 2 doses of IPV and are also scheduled to receive the other vaccine components of diphtheria/hepB/pertussis,acel/polio/tetanus vaccine (PEDIARIX).

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Vaccine should not be administered to any infant before the age of 6 weeks, or to individuals 7 years of age or older.

Dialysis

Data not available

See also...