Diclofenac Topical Dosage

This dosage information may not include all the information needed to use Diclofenac Topical safely and effectively. See additional information for Diclofenac Topical.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Keratosis

3% Gel: Apply amount sufficient to cover each actinic keratosis lesion twice daily and rub in gently for 60 to 90 days. Complete healing of lesions may not be evident for 30 days after discontinuation of therapy.

Usual Adult Dose for Osteoarthritis

1% Gel:
Apply the gel (4 g) to the affected foot or knee or ankle four times daily and rub in gently. Do not apply more than 16 g daily to any single joint of the lower extremities.

Apply the gel (2 g) to the affected hand or elbow or wrist four times daily and rub in gently. Do not apply more than 8 g daily to any single joint of the upper extremities.

Total dose should not exceed 32 g per day, over all affected joints.

Topical solution 1.5%:
10 drops at a time either directly onto the knee or first into the hand and then onto the knee. Spread around evenly around front, back, and sides of the knee. Repeat this procedure until 40 drops have been applied and the knee is completely covered with solution. Wash hands completely after administering product. Wait until the area is completely dry before covering with clothing or applying sunscreen, insect repellent, cosmetics, topical medications, or other substances.

Usual Adult Dose for Pain

1.3% topical patch:
Acute pain due to minor strains, sprains, and contusions:
Apply one patch to the most painful area twice a day.

Renal Dose Adjustments

Use with caution in patients with severe renal dysfunction.

Liver Dose Adjustments

Use with caution in patients with severe hepatic dysfunction.

Dose Adjustments

If severe dermatitis occurs, discontinue use until the dermatitis has subsided.

Dialysis

There are no data on the dialysis clearance of diclofenac topical; however, little removal is expected due to its high plasma protein binding (99%).

Other Comments

Diclofenac patches are contraindicated for use on damaged skin from any cause, including exudative dermatitis, eczema, infection lesions, burns, or wounds.

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