Diclofenac Topical Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Keratosis

3% Gel: Apply amount sufficient to cover each actinic keratosis lesion twice daily and rub in gently for 60 to 90 days. Complete healing of lesions may not be evident for 30 days after discontinuation of therapy.

Usual Adult Dose for Osteoarthritis

1% Gel:
Apply the gel (4 g) to the affected foot or knee or ankle four times daily and rub in gently. Do not apply more than 16 g daily to any single joint of the lower extremities.

Apply the gel (2 g) to the affected hand or elbow or wrist four times daily and rub in gently. Do not apply more than 8 g daily to any single joint of the upper extremities.

Total dose should not exceed 32 g per day, over all affected joints.

1.3% topical patch:
Acute pain due to minor strains, sprains, and contusions:
Apply one patch to the most painful area twice a day.

Topical solution 1.5%:
10 drops at a time either directly onto the knee or first into the hand and then onto the knee. Spread around evenly around front, back, and sides of the knee. Repeat this procedure until 40 drops have been applied and the knee is completely covered with solution.

Topical solution 2%:
Apply 40 mg (2 pump actuations) on each painful knee, 2 times daily. Apply directly to the knee or first into the hand and then onto the knee. Spread around front, back and sides of the knee evenly.

Usual Adult Dose for Pain

1% Gel:
Apply the gel (4 g) to the affected foot or knee or ankle four times daily and rub in gently. Do not apply more than 16 g daily to any single joint of the lower extremities.

Apply the gel (2 g) to the affected hand or elbow or wrist four times daily and rub in gently. Do not apply more than 8 g daily to any single joint of the upper extremities.

Total dose should not exceed 32 g per day, over all affected joints.

1.3% topical patch:
Acute pain due to minor strains, sprains, and contusions:
Apply one patch to the most painful area twice a day.

Topical solution 1.5%:
10 drops at a time either directly onto the knee or first into the hand and then onto the knee. Spread around evenly around front, back, and sides of the knee. Repeat this procedure until 40 drops have been applied and the knee is completely covered with solution.

Topical solution 2%:
Apply 40 mg (2 pump actuations) on each painful knee, 2 times daily. Apply directly to the knee or first into the hand and then onto the knee. Spread around front, back and sides of the knee evenly.

Renal Dose Adjustments

Use with caution in patients with severe renal dysfunction.

Liver Dose Adjustments

Use with caution in patients with severe hepatic dysfunction.

Dose Adjustments

If severe dermatitis occurs, discontinue use until the dermatitis has subsided.

Dialysis

There are no data on the dialysis clearance of diclofenac topical; however, little removal is expected due to its high plasma protein binding (99%).

Other Comments

-Diclofenac patches are contraindicated for use on damaged skin from any cause, including exudative dermatitis, eczema, infection lesions, burns, or wounds.
-Avoid showering/bathing for at least 30 minutes after application.
-Wash and dry hands after use.
-Do not apply to open wounds.
-Avoid contact with eyes and mucous membranes.
-Do not apply external heat and/or occlusive dressings to treated area(s).
-Avoid wearing clothing over the treated area(s) until the treated area(s) is dry.
-Protect the treated area(s) from sunlight.
-Wait until the treated area(s) is dry before applying sunscreen, insect repellant, lotion, moisturizer, cosmetics, or other topical medication to the same area(s).
-Until the treated area(s) is completely dry, avoid skin-to-skin contact between other people and the treated area(s).

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