Dextromethorphan / Quinidine Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Pseudobulbar Affect

dextromethorphan-quinidine 20 mg-10 mg:
Starting dose: one capsule daily by mouth for 7 days.
Maintenance dose: After 7 days, 1 capsule every 12 hours.

Renal Dose Adjustments

Dose adjustment is not required in patients with mild to moderate renal impairment. The pharmacokinetics have not been evaluated in patients with severe renal impairment; however, increases in dextromethorphan and/or quinidine levels are likely to be observed.

Liver Dose Adjustments

Dose adjustment is not required in patients with mild to moderate hepatic impairment. The pharmacokinetics have not been evaluated in patients with severe hepatic impairment; however, increases in dextromethorphan and/or quinidine levels are likely to be
observed.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

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