Dextromethorphan / Promethazine Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

Usual Adult Dose for Cold Symptoms

5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

Usual Adult Dose for Cough

5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

Usual Pediatric Dose for Allergic Rhinitis

12 years or older:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

6 years to 11 years:
2.5 to 5 mL orally every 4 to 6 hours, not to exceed 20 mL in 24 hours.

2 years to 5 years:
1.25 to 2.5 mL orally every 4 to 6 hours, not to exceed 10 mL in 24 hours.

Usual Pediatric Dose for Cold Symptoms

12 years or older:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

6 years to 11 years:
2.5 to 5 mL orally every 4 to 6 hours, not to exceed 20 mL in 24 hours.

2 years to 5 years:
1.25 to 2.5 mL orally every 4 to 6 hours, not to exceed 10 mL in 24 hours.

Usual Pediatric Dose for Cough

12 years or older:
5 mL orally every 4 to 6 hours, not to exceed 30 mL in 24 hours.

6 years to 11 years:
2.5 to 5 mL orally every 4 to 6 hours, not to exceed 20 mL in 24 hours.

2 years to 5 years:
1.25 to 2.5 mL orally every 4 to 6 hours, not to exceed 10 mL in 24 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Promethazine hydrochloride should not be used in pediatric patients less than 2 years of age because of the potential for fatal respiratory depression. Postmarketing cases of respiratory depression, including fatalities, have been reported with use of promethazine hydrochloride in pediatric patients less than 2 years of age. A wide range of weight-based doses of promethazine hydrochloride have resulted in respiratory depression in these patients.

Caution should be exercised when administering promethazine hydrochloride to pediatric patients 2 years of age and older. It is recommended that the lowest effective dose of promethazine hydrochloride be used in pediatric patients 2 years of age and older and concomitant administration of other drugs with respiratory depressant effects be avoided.

Dialysis

Data not available

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