Dextromethorphan / Guaifenesin / Pseudoephedrine Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough and Nasal Congestion

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-175 mg-30 mg/5 mL oral liquid:
10 mL orally every 8 hours
Maximum dose: 30 mL daily

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-200 mg-30 mg/5 mL oral liquid:
10 mL orally every 6 hours
Maximum dose: 4 doses daily

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-400 mg-60 mg oral tablet:
1 tablet orally every 4 hours
Maximum dose: 4 tablets daily

Dextromethorphan/guaifenesin/pseudoephedrine 20 mg-400 mg-60 mg oral tablet:
1 tablet orally every 4 to 6 hours
Maximum dose: 4 tablets daily

Dextromethorphan/guaifenesin/pseudoephedrine 30 mg-400 mg-30 mg oral tablet:
1 tablet orally every 6 hours
Maximum dose: 4 tablets daily

Dextromethorphan/guaifenesin/pseudoephedrine 30 mg-400 mg-60 mg oral tablet:
1 tablet orally every 6 hours
Maximum dose: 4 tablets daily

Duration of therapy: 7 days

Usual Pediatric Dose for Cough and Nasal Congestion

Dextromethorphan/guaifenesin/pseudoephedrine 2.5 mg-25 mg-7.5 mg/1 mL solution/drops:
2 to 5 years (24 to 47 pounds): 2 mL orally every 4 to 6 hours
Maximum dose: 4 doses daily

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-175 mg-30 mg/5 mL oral liquid:
12 years or older: 10 mL orally every 8 hours
6 to 11 years: 5 mL orally every 8 hours
Maximum dose: 3 doses daily

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-200 mg-30 mg/5 mL oral liquid:
12 years or older: 10 mL orally every 6 hours
6 to 11 years: 5 mL orally every 6 hours
Maximum dose: 4 doses daily

Dextromethorphan/guaifenesin/pseudoephedrine 15 mg-400 mg-60 mg oral tablet:
12 years or older: 1 tablet orally every 4 hours
6 to 11 years: 1/2 tablet orally every 4 hours
Maximum dose: 4 doses daily

Dextromethorphan/guaifenesin/pseudoephedrine 20 mg-400 mg-60 mg oral tablet:
12 years or older: 1 tablet orally every 4 to 6 hours
Maximum dose: 4 tablets daily

Dextromethorphan/guaifenesin/pseudoephedrine 30 mg-400 mg-30 mg oral tablet:
12 years or older: 1 tablet orally every 6 hours
Maximum dose: 4 tablets daily

Dextromethorphan/guaifenesin/pseudoephedrine 30 mg-400 mg-60 mg oral tablet:
12 years or older: 1 tablet orally every 6 hours not to exceed 4 tablets daily
6 to 11 years: ½ tablet every 6 hours
Maximum dose: 4 doses daily

Duration of therapy: 7 days

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for dosing related precautions.

Dialysis

Data not available for dextromethorphan and guaifenesin
Pseudoephedrine is slightly dialyzable; however, no dose adjustment guidelines have been reported.

Other Comments

General: The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

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