Depo-SubQ Provera 104 Dosage
Generic name: medroxyprogesterone acetate
Dosage form: injection, suspension
See also:
This dosage information does not include all the information needed to use Depo-SubQ Provera 104 safely and effectively. See full prescribing information for Depo-SubQ Provera 104.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
CONTRACEPTION AND ENDOMETRIOSIS INDICATIONS
Route of Administration
depo-subQ provera 104 must be given by subcutaneous injection into the anterior thigh or abdomen, once every 3 months (12 to 14 weeks). depo-subQ provera 104 is not formulated for intramuscular injection. Dosage does not need to be adjusted for body weight. The pre-filled syringe of depo-subQ provera 104 must be vigorously shaken just before use to create a uniform suspension.
First Injection
Ensure that the patient is not pregnant at the time of the first injection. For women who are sexually active and having regular menses, the first injection should be given only during the first 5 days of a normal menstrual period. Women who are breast-feeding may have their first injection during or after their sixth postpartum week.
IF USING FOR CONTRACEPTION AND SWITCHING FROM ANOTHER METHOD
When switching from other contraceptive methods, depo-subQ provera 104 should be given in a manner that ensures continuous contraceptive coverage. For example, patients switching from combined (estrogen plus progestin) contraceptives should have their first injection of depo-subQ provera 104 within 7 days after the last day of using that method (7 days after taking the last active pill, removing the patch or ring). Similarly, contraceptive coverage will be maintained in switching from Depo-Provera CI (150 mg) to depo-subQ provera 104, provided the next injection is given within the prescribed dosing period for Depo-Provera CI (150 mg).
IF USING FOR TREATMENT OF ENDOMETRIOSIS
Treatment for longer than two years is not recommended, due to the impact of long-term depo-subQ provera 104 on bone mineral density. If symptoms return after discontinuation of treatment, bone mineral density should be evaluated prior to retreatment.
Instructions for Use of depo-subQ provera 104
FOR SUBCUTANEOUS ADMINISTRATION ONLY
Please read these instructions carefully. It is very important that the entire dose of depo-subQ provera 104 is given.
Getting ready
Do not refrigerate. Ensure that the medication is at room temperature prior to injection (to ensure appropriate viscosity of the suspension). Make sure the following components are available.

depo-subQ provera 104, as with other parenteral drug products, should be inspected visually for particulate matter and discoloration prior to administration.
Step 1: Choosing & preparing the injection Area
Choose the injection area.
|
Preferred injection areas:![]() Upper thigh or abdomen |
Use an alcohol pad to wipe the skin in the injection area you have chosen.
|
Step 2: Syringe preparation
| Carefully remove the needle and syringe from the packaging. Hold the syringe firmly by the barrel, with the barrel pointing upward.
|
![]() |
Hold the syringe barrel firmly.
|
Shake vigorously for 1 minute![]() |
Hold the syringe barrel firmly.
|
![]() |
|
![]() |
|
![]() |
|
Step 3: Injecting the dose
| Gently grasp and squeeze a large area of skin in the chosen injection area between the thumb and forefinger, pulling it away from the body. | |
Insert the needle at a 45 degree angle so that most of the needle is in the fatty tissue.
|
|
Inject the medication slowly until the syringe is empty.
|
Inject slowly (5–7 seconds) |
Step 4: Disposing the needle and syringe
| After completing the injection, remove the needle from the skin and activate the safety shield. | |
| Position shield about 40°– 45°. With a firm quick motion, press down against a flat surface until a click is heard or felt. | |
| If uncertain that the safety shield is fully engaged, repeat this step. | |
Use a clean cotton pad to press lightly on the injection area for a few seconds.
|
|
| Following the administration of each dose, the used syringe should be discarded in a safe and proper manner. | |
| Keep away from children. | |
See also...
- Depo-subQ provera 104 Side Effects
- Depo-subQ provera 104 Drug Interactions
- Depo-Provera (medroxyprogesterone acetate) injection, suspension dosage information
- Depo-Provera (medroxyprogesterone) consumer information
- Medroxyprogesterone dosage information
- Medroxyprogesterone consumer information
- Provera (medroxyprogesterone acetate) tablet dosage information








