Demeclocycline Dosage

This dosage information may not include all the information needed to use Demeclocycline safely and effectively. See additional information for Demeclocycline.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for SIADH

Initial dose: 300 mg orally 4 times a day.
Maintenance dose: 300 to 900 mg/day orally or the lowest effective dosage to prevent hyponatremia.

Renal Dose Adjustments

Caution and dose reduction or interval prolongation should be considered in patients with renal impairment.

Liver Dose Adjustments

Caution and dose reduction or interval prolongation should be considered in patients with hepatic impairment.

Dialysis

Demeclocycline is not significantly removed by hemodialysis or peritoneal dialysis. Caution and dose reduction or interval prolongation should be considered in patients with renal impairment.

Other Comments

Demeclocycline is approved by the FDA for the treatment of a variety of infections due to susceptible organisms; however, it is rarely, if ever, used clinically as an antibiotic.

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