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Daunorubicin Liposomal Dosage

This dosage information may not include all the information needed to use Daunorubicin Liposomal safely and effectively. See additional information for Daunorubicin Liposomal.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Kaposi's Sarcoma

For first line cytotoxic therapy for advanced HIV-associated Kaposi's sarcoma. (Note: Daunorubicin liposomal is not recommended for use in patients with less than advanced HIV-related Kaposi's sarcoma.

If the patient has an acceptable benefit-cardiac risk ratio and adequate blood cell counts, then the recommended dose is: 40 mg/m2 infused intravenously over 60 minutes every 2 weeks,

Renal Dose Adjustments

If the serum creatinine is >3 mg/dL, then 1/2 of the normal dose is recommended

Liver Dose Adjustments

If the serum bilirubin is 1.2 to 3 mg/dL, then 3/4 of the normal dose is recommended.

If the serum bilirubin is >3 mg/dL, then 1/2 of the normal dose is recommended

Precautions

Safety has not been established in patients with pre-existing renal or hepatic dysfunction.

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