Clofibrate Dosage
This dosage information may not include all the information needed to use Clofibrate safely and effectively. See additional information for Clofibrate.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Hyperlipidemia
500 mg orally 4 times a day.
Renal Dose Adjustments
CrCl < 10 mL/min: Not recommended.
CrCl 10 to 50 mL/min: 500 mg orally every 12 to 18 hours.
CrCl > 50 mL/min: 500 mg orally every 6 to 12 hours.
Liver Dose Adjustments
Clofibrate is considered contraindicated in patients with significant hepatic dysfunction.
Precautions
It is contraindicated in patients with clinically significant hepatic dysfunction.
Dialysis
Clofibrate has been shown to have an average elimination half-life of 133 hours in patients undergoing hemodialysis.
Other Comments
Some patients may respond to lower doses.
