Chlorpheniramine / Phenylephrine Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Allergic Rhinitis

Immediate-release tablets: 1 tablet (2 mg-5 mg) every 4 to 6 hours as needed or 1 tablet (4 mg-10 mg or 3 mg-10 mg) every 4 hours as needed. Not to exceed 6 doses in 24 hours.
Immediate-release liquid: 5 mL (4 mg-10 mg/5 mL) or (4 mg-12.5 mg/5 mL) 3 to 4 times a day as needed

Sustained-release tablets: 1 tablet (8 mg-20mg) or (9 mg-25 mg) every 12 hours as needed.
or 1 to 2 tablet(s) (4 mg-20mg) every 12 hours as needed

Sustained-release suspension:
chlorpheniramine-phenylephrine (3 mg-7.5 mg/ 5 mL) extended release suspension
15 mL orally every 12 hours as needed.

Usual Adult Dose for Cold Symptoms

Immediate-release tablets: 1 tablet (2 mg-5 mg) every 4 to 6 hours as needed or 1 tablet (4 mg-10 mg or 3 mg-10 mg) every 4 hours as needed. Not to exceed 6 doses in 24 hours.
Immediate-release liquid: 5 mL (4 mg-10 mg/5 mL) or (4 mg-12.5 mg/5 mL) 3 to 4 times a day as needed

Sustained-release tablets: 1 tablet (8 mg-20mg) or (9 mg-25 mg) every 12 hours as needed.
or 1 to 2 tablet(s) (4 mg-20mg) every 12 hours as needed

Sustained-release suspension:
chlorpheniramine-phenylephrine (3 mg-7.5 mg/ 5 mL) extended release suspension
15 mL orally every 12 hours as needed.

Usual Pediatric Dose for Allergic Rhinitis

chlorpheniramine-phenylephrine (1 mg-3.5 mg/mL) oral drops:
6 months to 11 months: 0.75 mL orally 4 times a day.
1 year to 2 years: 1 mL orally 4 times a day.

chlorpheniramine-phenylephrine (1 mg-2 mg/mL) oral drops:
2 years to 5 years: 1 mL orally every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours.
6 years to 12 years: 2 mL orally every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours.

chlorpheniramine-phenylephrine 1 mg-2.5 mg/ 5 mL oral drops:
6 years to 12 years: 10 mL orally every 4 hours. Do not exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine 2 mg-5 mg/ml oral drops:
2 years to 5 years: 0.5 mL every 4 hours. Do not exceed 6 doses in 24 hours.
6 years to 12 years: 1 mL every 4 hours. Do not exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine (3 mg-7.5 mg/ 5 mL) extended release suspension:
2 to 5 years: 1.25 to 2.5 ml orally every 12 hours as needed.
6 to 11 years: 2.5 to 5 ml orally every 12 hours as needed.
12 years or older: 15 ml orally every 12 hours as needed.

chlorpheniramine-phenylephrine (4 mg-7.5 mg/ 20 mL) extended release suspension:
2 to 5 years: 2.5 ml orally every 12 hours as needed.
6 to 11 years: 5 ml orally every 12 hours as needed.
12 years or older: 10 ml orally every 12 hours as needed.

chlorpheniramine-phenylephrine (4 mg-10 mg or 3 mg-10 mg) oral tablet:
6 to 11 years: one half tablet orally every 4 hours as needed.
12 years or older: one tablet orally every 4 hours as needed.
Not to exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine (4 mg-12.5 mg/ 5 mL) oral syrup;
2 to 5 years: 1.25 ml orally every 4 hours to 6 hours, not to exceed 7.5 mL in 24 hours.
6 to 11 years: 2.5 ml orally every 4 hours to 6 hours, not to exceed 15 mL in 24 hours.
12 years or older: 5 ml orally every 4 hours to 6 hours, not to exceed 30 mL in 24 hours.

chlorpheniramine-phenylephrine (4.5 mg-5 mg/ 5 mL) extended release suspension:
2 to 5 years: 2.5 ml to 5 mL orally every 12 hours.
6 to 11 years: 2.5 ml to 10 mL orally every 12 hours.

chlorpheniramine-phenylephrine (4 mg-20 mg) extended release capsule:
6 to 12 years: one capsule orally every 12 hours, not to exceed 2 capsules in 24 hours.
12 years or older: two capsules orally every 12 hours, not to exceed 4 capsules in 24 hours.

chlorpheniramine-phenylephrine (8 mg-20 mg) extended release tablet:
6 to 12 years: one-half tablet orally every 12 hours.
12 years or older: one tablet orally every 12 hours.

Usual Pediatric Dose for Cold Symptoms

chlorpheniramine-phenylephrine (1 mg-3.5 mg/mL) oral drops:
6 months to 11 months: 0.75 mL orally 4 times a day.
1 year to 2 years: 1 mL orally 4 times a day.

chlorpheniramine-phenylephrine (1 mg-2 mg/mL) oral drops:
2 years to 5 years: 1 mL orally every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours.
6 years to 12 years: 2 mL orally every 4 to 6 hours as needed. Do not exceed 4 doses in 24 hours.

chlorpheniramine-phenylephrine 1 mg-2.5 mg/ 5 mL oral drops:
6 years to 12 years: 10 mL orally every 4 hours. Do not exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine 2 mg-5 mg/ml oral drops:
2 years to 5 years: 0.5 mL every 4 hours. Do not exceed 6 doses in 24 hours.
6 years to 12 years: 1 mL every 4 hours. Do not exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine (3 mg-7.5 mg/ 5 mL) extended release suspension:
2 to 5 years: 1.25 to 2.5 ml orally every 12 hours as needed.
6 to 11 years: 2.5 to 5 ml orally every 12 hours as needed.
12 years or older: 15 ml orally every 12 hours as needed.

chlorpheniramine-phenylephrine (4 mg-7.5 mg/ 20 mL) extended release suspension:
2 to 5 years: 2.5 ml orally every 12 hours as needed.
6 to 11 years: 5 ml orally every 12 hours as needed.
12 years or older: 10 ml orally every 12 hours as needed.

chlorpheniramine-phenylephrine (4 mg-10 mg or 3 mg-10 mg) oral tablet:
6 to 11 years: one half tablet orally every 4 hours as needed.
12 years or older: one tablet orally every 4 hours as needed.
Not to exceed 6 doses in 24 hours.

chlorpheniramine-phenylephrine (4 mg-12.5 mg/ 5 mL) oral syrup;
2 to 5 years: 1.25 ml orally every 4 hours to 6 hours, not to exceed 7.5 mL in 24 hours.
6 to 11 years: 2.5 ml orally every 4 hours to 6 hours, not to exceed 15 mL in 24 hours.
12 years or older: 5 ml orally every 4 hours to 6 hours, not to exceed 30 mL in 24 hours.

chlorpheniramine-phenylephrine (4.5 mg-5 mg/ 5 mL) extended release suspension:
2 to 5 years: 2.5 ml to 5 mL orally every 12 hours.
6 to 11 years: 2.5 ml to 10 mL orally every 12 hours.

chlorpheniramine-phenylephrine (4 mg-20 mg) extended release capsule:
6 to 12 years: one capsule orally every 12 hours, not to exceed 2 capsules in 24 hours.
12 years or older: two capsules orally every 12 hours, not to exceed 4 capsules in 24 hours.

chlorpheniramine-phenylephrine (8 mg-20 mg) extended release tablet:
6 to 12 years: one-half tablet orally every 12 hours.
12 years or older: one tablet orally every 12 hours.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

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