Chlorpheniramine/Methscopolamine/Pseudoephedrine Dosage

Usual Adult Dose for Allergic Rhinitis

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
1 tablet orally per day.

Usual Adult Dose for Nasal Congestion

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
1 tablet orally per day.

Usual Adult Dose for Sinus Symptoms

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
1 tablet orally per day.

Usual Pediatric Dose for Allergic Rhinitis

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
6 to 11 years: 1 tablet orally every 12 hours not to exceed 2 doses daily.
12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
12 years or older: 1 tablet orally per day.

Usual Pediatric Dose for Nasal Congestion

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
6 to 11 years: 1 tablet orally every 12 hours not to exceed 2 doses daily.
12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
12 years or older: 1 tablet orally per day.

Usual Pediatric Dose for Sinus Symptoms

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-30 mg/ 5 mL oral syrup:
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 5 to 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/methscopolamine/PSE 4 mg-1.25 mg-60 mg oral tablet, extended release:
6 to 11 years: 1 tablet orally every 12 hours not to exceed 2 doses daily.
12 years or older: 1 to 2 tablets orally every 12 hours not to exceed 2 doses daily.

Chlorpheniramine/methscopolamine/PSE 6 mg-2.5 mg-120 mg oral tablet, extended release:
12 years or older: 1 tablet orally per day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

See also...