Chlorpheniramine / Hydrocodone / Pseudoephedrine Dosage

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Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cough and Nasal Congestion

Chlorpheniramine/hydrocodone/pseudoephedrine 2 mg-5 mg-30 mg oral capsule:
1 to 2 capsules orally every 8 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 2.5 mg-1.67 mg-17.5 mg/5 mL oral liquid:
10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/hydrocodone/pseudoephedrine 2.5 mg-1.67 mg-20 mg/5 mL oral liquid:
10 mL orally every 4 to 6 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 4 mg-5 mg-30 mg/5 mL oral suspension, extended release:
5 to 10 mL orally every 12 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 4 mg-5 mg-40 mg/5 mL oral syrup:
5 mL orally 3 to 4 times daily not to exceed 4 doses per day.

Chlorpheniramine/hydrocodone/pseudoephedrine 4 mg-5 mg-60 mg/5 mL oral liquid:
5 mL orally every 4 to 6 hours not to exceed 4 doses per day.

Usual Pediatric Dose for Cough and Nasal Congestion

Chlorpheniramine/hydrocodone/pseudoephedrine 2 mg-5 mg-30 mg oral capsule:
6 to 11 years: 1 capsule orally every 8 hours.
12 years or older: 1 to 2 capsules orally every 8 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 2.5 mg-1.67 mg-17.5 mg/5 mL oral liquid:
2 to 5 years: 2.5 mL orally every 4 to 6 hours not to exceed 10 mL daily.
6 to 11 years: 5 mL orally every 4 to 6 hours not to exceed 20 mL daily.
12 years or older: 10 mL orally every 4 to 6 hours not to exceed 40 mL daily.

Chlorpheniramine/hydrocodone/pseudoephedrine 2.5 mg-1.67 mg-20 mg/5 mL oral liquid:
2 to 5 years: 2.5 mL orally every 4 to 6 hours.
6 to 11 years: 5 mL orally every 4 to 6 hours.
12 years or older: 10 mL orally every 4 to 6 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 4 mg-5 mg-30 mg/5 mL oral suspension, extended release:
2 to 5 years: 2.5 mL orally every 12 hours.
6 to 11 years: 2.5 to 5 mL orally every 12 hours.
12 years or older: 5 to 10 mL orally every 12 hours.

Chlorpheniramine/hydrocodone/pseudoephedrine 4 mg-5 mg-40 mg/5 mL oral syrup:
6 to 11 years: 2.5 mL orally 3 to 4 times daily not to exceed 4 doses per day.
12 years or older: 5 mL orally 3 to 4 times daily not to exceed 4 doses per day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

The FDA has not approved use of over-the-counter cough and cold medications to children aged less than 2 years, and proper dosing for children in this age group has not been studied. Clinicians should be aware of the risk for serious illness or fatal overdose from administration of cough and cold medications to children aged less than 2 years. Clinicians should be certain that caregivers understand 1) the importance of administering cough and cold medications only as directed and 2) the risk for overdose if they administer additional medications that might contain the same ingredient.

Dialysis

Data not available

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