Ceftin Dosage

Generic name: cefuroxime axetil
Dosage form: tablet, film coated - powder, for suspension

See also:

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

NOTE: CEFTIN TABLETS AND CEFTIN FOR ORAL SUSPENSION ARE NOT BIOEQUIVALENT AND ARE NOT SUBSTITUTABLE ON A MILLIGRAMPERMILLIGRAM BASIS (SEE CLINICAL PHARMACOLOGY).

Table 9. CEFTIN Tablets

(May be administered without regard to meals.)

Population/Infection

Dosage

Duration (days)

Adolescents and Adults (13 years and older)

Pharyngitis/tonsillitis

250 mg twice daily

10

Acute bacterial maxillary sinusitis

250 mg twice daily

10

Acute bacterial exacerbations of chronic bronchitis

250 or 500 mg twice daily

10a

Secondary bacterial infections of acute bronchitis

250 or 500 mg twice daily

5-10

Uncomplicated skin and skin-structure infections

250 or 500 mg twice daily

10

Uncomplicated urinary tract infections

250 mg twice daily

7-10

Uncomplicated gonorrhea

1,000 mg once daily

single dose

Early Lyme disease

500 mg twice daily

20

Pediatric Patients (who can swallow tablets whole)

Acute otitis media

250 mg twice daily

10

Acute bacterial maxillary sinusitis

250 mg twice daily

10

 
a The safety and effectiveness of CEFTIN administered for less than 10 days in patients with acute exacerbations of chronic bronchitis have not been established.

CEFTIN for Oral Suspension

CEFTIN for Oral Suspension may be administered to pediatric patients ranging in age from 3 months to 12 years, according to dosages in Table 10:

Table 10. CEFTIN for Oral Suspension

(Must be administered with food. Shake well each time before using.)

Population/Infection

Dosage

Daily Maximum Dose

Duration (days)

Pediatric Patients (3 months to 12 years)

Pharyngitis/tonsillitis

20 mg/kg/day divided twice daily

500 mg

10

Acute otitis media

30 mg/kg/day divided twice daily

1,000 mg

10

Acute bacterial maxillary sinusitis

30 mg/kg/day divided twice daily

1,000 mg

10

Impetigo

30 mg/kg/day divided twice daily

1,000 mg

10

Patients with Renal Impairment

Because cefuroxime is eliminated primarily by the kidney, a dosage interval adjustment is required for patients whose creatinine clearance is <30 mL/min, as listed in Table 11.

Table 11. Dosing in Patients with Renal Impairment

Creatinine Clearance (mL/min)

Recommended Dosage

≥30

No dosage adjustment

10 to <30

Standard individual dose given every 24 hours

<10 (without hemodialysis)

Standard individual dose given every 48 hours

Hemodialysis

A single additional standard dose should be given at the end of each dialysis

Directions for Mixing CEFTIN for Oral Suspension

Prepare a suspension at the time of dispensing as follows:

1.
Shake the bottle to loosen the powder.
2.
Remove the cap.
3.
Add the total amount of water for reconstitution (see Table 12) and replace the cap.
4.
Invert the bottle and vigorously rock the bottle from side to side so that water rises through the powder.
5.
Once the sound of the powder against the bottle disappears, turn the bottle upright and vigorously shake it in a diagonal direction.
Table 12. Amount of Water Required for Reconstitution of Labeled Volumes of CEFTIN for Oral Suspension

CEFTIN for Oral Suspension

Labeled Volume

After Reconstitution

Amount of Water Required

for Reconstitution

125 mg/5 mL

100 mL

37 mL

250 mg/5 mL

50 mL

19 mL

100 mL

35 mL

 

NOTE: SHAKE THE ORAL SUSPENSION WELL BEFORE EACH USE. Replace cap securely after each opening. Store the reconstituted suspension between 2° and 8°C (36° and 46°F) (in a refrigerator). DISCARD AFTER 10 DAYS.

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