Cefixime Dosage
This dosage information may not include all the information needed to use Cefixime safely and effectively. See additional information for Cefixime.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
- Upper Respiratory Tract Infection
- Otitis Media
- Cystitis
- Gonococcal Infection - Uncomplicated
- Pyelonephritis
- Gonococcal Infection - Disseminated
- Bronchitis
- Sinusitis
- Pneumonia
- Tonsillitis/Pharyngitis
Usual Pediatric Dose for:
Additional dosage information:
Usual Adult Dose for Upper Respiratory Tract Infection
400 mg orally once a day for 10 days
Usual Adult Dose for Otitis Media
400 mg orally once a day for 10 to 14 days
Usual Adult Dose for Cystitis
400 mg orally once a day for 3 to 7 days
Usual Adult Dose for Gonococcal Infection - Uncomplicated
Uncomplicated infections of the cervix, urethra, or rectum: 400 mg orally one time
Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin is also recommended to treat possible concurrent chlamydial infection.
The patient's sexual partner(s) should also be evaluated/treated.
Usual Adult Dose for Pyelonephritis
400 mg orally once a day for 14 days
Usual Adult Dose for Gonococcal Infection - Disseminated
400 mg orally twice a day; the Centers for Disease Control and Prevention currently recommend 500 mg (suspension) orally twice a day
Initial therapy for disseminated gonococcal infections requires parenteral therapy which should be continued for 24 to 48 hours after clinical improvement is observed. Oral therapy may then be administered to complete a total course of at least 1 week.
Doxycycline therapy for 7 days (if not pregnant) or single dose azithromycin is also recommended to treat possible concurrent chlamydial infection.
The patient's sexual partner(s) should also be evaluated/treated.
Usual Adult Dose for Bronchitis
400 mg orally once a day for 7 to 10 days
Usual Adult Dose for Sinusitis
400 mg orally once a day for 10 to 14 days
Longer courses of therapy, sometimes 3 to 4 weeks, may be required for refractory or recurrent cases.
Usual Adult Dose for Pneumonia
400 mg orally once a day for 10 days
Usual Adult Dose for Tonsillitis/Pharyngitis
400 mg orally once a day for 10 days
Usual Pediatric Dose for Otitis Media
8 mg/kg/day orally (use suspension) given in a single daily dose or as 4 mg/kg orally every 12 hours
Children over 50 kg or older than 12 years should be administered the recommended adult dose.
Usual Pediatric Dose for Urinary Tract Infection
8 mg/kg orally every 12 hours on day one, then 8 mg/kg orally every 24 hours days 2 to 14
Usual Pediatric Dose for STD Prophylaxis
Prophylaxis following sexual victimization: 8 mg/kg orally in a single dose (400 mg maximum) plus azithromycin 20 mg/kg (1 g maximum) as a single oral dose
Also begin or complete hepatitis B virus immunization and consider prophylaxis for trichomoniasis and bacterial vaginosis.
Renal Dose Adjustments
CrCl 21 to 59 mL/min: May receive 75% of the standard dosage at the standard dosing interval
CrCl 20 mL/min or less: May receive 50% of the standard dosage at the standard dosing interval
Liver Dose Adjustments
Data not available
Dialysis
Hemodialysis: May be given 75% of the standard dosage at the standard dosing interval
CAPD: May be given 50% of the standard dosage at the standard dosing interval
Neither hemodialysis nor peritoneal dialysis remove significant amounts of drug from the body.
Other Comments
In the treatment of infections due to S pyogenes, a therapeutic dose should be administered for at least 10 days.
