Calcipotriene Topical Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Psoriasis

Plaque psoriasis:
Cream: Apply a thin layer to affected areas twice a day.
Ointment: Apply a thin layer to affected areas once or twice a day.

Plaque psoriasis of the scalp and body:
Foam: Apply a thin layer to affected areas twice a day.

Chronic, moderately severe psoriasis of the scalp:
Solution: After combing the hair to remove scaly debris and then suitably parting, apply to lesions twice a day, taking care to prevent the solution spreading onto the forehead.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Calcipotriene topical is contraindicated in patients with known hypercalcemia or evidence of vitamin D toxicity. Calcipotriene topical solution is contraindicated in patients with acute psoriatic eruptions. Calcipotriene topical cream and ointment should not be used on the face.

The propellant in calcipotriene topical foam is flammable. Patients should be instructed to avoid fire, flame, and smoking during and immediately after application.

Transient, rapidly reversible elevation of serum calcium has been reported with calcipotriene topical. If serum calcium becomes elevated above the normal range, therapy should be discontinued until calcium levels have returned to normal.

Calcipotriene topical cream, ointment, and solution may cause irritation of lesions and surrounding uninvolved skin. Calcipotriene topical should be discontinued if irritation develops.

Patients that apply calcipotriene topical to exposed portions of the body should avoid excessive exposure to either natural or artificial sunlight. Physicians may wish to limit or avoid use of phototherapy in patients that use calcipotriene topical.

Safety and effectiveness of calcipotriene topical cream, ointment, or solution have not been established in dermatoses other than psoriasis. Calcipotriene topical foam has not been evaluated in patients with erythrodermic, exfoliative, or pustular psoriasis.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

Calcipotriene topical foam should be applied to the scalp when hair is dry. After parting the hair, it should be applied directly on the affected area.

Calcipotriene topical should be rubbed in gently and completely. Patients should wash their hands after application of calcipotriene topical cream, ointment, or solution. Patients should wash their hands after applying calcipotriene topical foam unless their hands are the affected site.

Calcipotriene topical is only intended for topical use (not for oral, ophthalmic, or intravaginal use). Patients using calcipotriene topical should be advised to avoid contact with the eyes and face.

The safety and efficacy has primarily been studied in patients treated up to 8 weeks. One study in a small group and one larger multicenter trial reported safety and efficacy up to 6 months and 1 year, respectively.

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