Bumetanide Dosage

This dosage information may not include all the information needed to use Bumetanide safely and effectively. See additional information for Bumetanide.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Ascites

Oral: 0.5 to 2 mg once a day.
IV or IM: 0.5 to 1 mg once.
Continuous IV infusion: 1 mg/hour up to 12 mg/day.

Usual Adult Dose for Edema

Oral: 0.5 to 2 mg once a day.
IV or IM: 0.5 to 1 mg once.
Continuous IV infusion: 1 mg/hour up to 12 mg/day.

Usual Adult Dose for Pulmonary Edema

Oral: 0.5 to 2 mg once a day.
IV or IM: 0.5 to 1 mg once.
Continuous IV infusion: 1 mg/hour up to 12 mg/day.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Patients with cirrhosis and ascites should be given smaller doses of bumetanide due to the risk of altered electrolyte balance, which can lead to hepatic encephalopathy.

Dose Adjustments

Oral doses may be titrated every 4 hours.
IV doses may be titrated every 2 to 3 hours.
Patients with edema often benefit from alternate day or every 3 to 4 day therapy.
Patients with liver disease and renal dysfunction should have dose adjustments made cautiously.

Precautions

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

The maximum recommended dose is 10 mg/day or 12 mg/12 hours continuous IV infusion.

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