Aygestin Dosage

Generic name: norethindrone acetate
Dosage form: tablet

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Therapy with AYGESTIN (norethindrone acetate tablets, USP) must be adapted to the specific indications and therapeutic response of the individual patient.

Secondary amenorrhea, abnormal uterine bleeding due to hormonal imbalance in the absence of organic pathology

2.5 to 10 mg AYGESTIN (norethindrone acetate tablets, USP) may be given daily for 5 to 10 days to produce secretory transformation of an endometrium that has been adequately primed with either endogenous or exogenous estrogen.

Progestin withdrawal bleeding usually occurs within three to seven days after discontinuing AYGESTIN (norethindrone acetate tablets, USP) therapy. Patients with a past history of recurrent episodes of abnormal uterine bleeding may benefit from planned menstrual cycling with AYGESTIN (norethindrone acetate tablets, USP).

Endometriosis

Initial daily dosage of 5 mg AYGESTIN (norethindrone acetate tablets, USP) for two weeks. Dosage should be increased by 2.5 mg per day every two weeks until 15 mg per day of AYGESTIN (norethindrone acetate tablets, USP) is reached. Therapy may be held at this level for six to nine months or until annoying breakthrough bleeding demands temporary termination.

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