Altoprev Dosage

Generic name: lovastatin
Dosage form: tablet, extended release

This dosage information does not include all the information needed to use Altoprev safely and effectively. See full prescribing information for Altoprev.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

2.1 Hyperlipidemia (Heterozygous Familial and Nonfamilial) and Mixed Dyslipidemia (Fredrickson Types IIa and IIb)

The recommended dosing range is 20-60 mg/day, in single doses taken in the evening at bedtime. 

2.2   Elderly Patients

The usual recommended starting dose in elderly patients (age≥65 years) is 20 mg once a day given in the evening at bedtime. Higher doses should be used only after careful consideration of the potential risks and benefits [see Use in Specific Populations (8.5) and Warnings and Precautions, Skeletal Muscle Effects (5.1)].

2.3   Co-administration with Other Drugs

Patients Taking Danazol, Diltiazem, Dronedarone, or Verapamil
The dose of Altoprev should not exceed 20 mg/day [see Warnings and Precautions, Skeletal Muscle Effects (5.1)].

Patients Taking Amiodarone

The dose of Altoprev should not exceed 40 mg/day. [see Warnings and Precautions, Skeletal Muscle Effects (5.1) and Drug Interactions (7.6)].

2.4   Dosage in Patients With Renal Impairment

In patients with severe renal impairment (creatinine clearance <30 mL/min), dosage increases above 20 mg/day should only be considered if the expected benefit exceeds the increased risk of myopathy/rhabdomyolysis.  [see Warnings and Precautions, Skeletal Muscle Effects (5.1) and Clinical Pharmacology, Pharmacokinetics (12.3)].

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