Acetaminophen / Diphenhydramine / Phenylephrine Dosage

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Cold Symptoms

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg oral tablet, or
Acetaminophen/diphenhydramine/phenylephrine 325 mg-25 mg-5 mg oral tablet:
2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/15 mL oral syrup:
30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg oral powder for reconstitution (one packet):
one packet dissolved in 8 oz hot water orally every 4 hours; sip while hot. Consume entire drink within 10 to 15 minutes. Do not exceed 6 packets in 24 hours.

Acetaminophen/diphenhydramine/phenylephrine 160 mg-6.25 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.
Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/10 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.
Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg/20 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.

Usual Pediatric Dose for Cold Symptoms

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg oral tablet:
12 yrs or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.
6 yrs to 11 yrs: 1 tablet orally every 4 hours not to exceed 5 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-25 mg-5 mg oral tablet:
12 yrs or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/15 mL oral syrup
12 yrs or older: 30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg oral powder for reconstitution (one packet):
12 yrs or older: one packet dissolved in 8 oz hot water orally every 4 hours; sip while hot. Consume entire drink within 10 to 15 minutes. Do not exceed 6 packets in 24 hours.

Acetaminophen/diphenhydramine/phenylephrine 160 mg-6.25 mg-2.5 mg/5 mL oral liquid:
12 yrs or older: 20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.
Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/10 mL oral liquid:
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.
6 years to under 12 years of age: 10 mL every 4 hours not to exceed 5 doses in any 24 hour period.
Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg/20 mL oral liquid:
12 years or older: 20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

Other Comments

Severe liver damage may occur if taken with other drugs containing acetaminophen.

Store oral liquid at room temperature; do not refrigerate.

Hide
(web3)