Acetaminophen/Diphenhydramine/Phenylephrine Dosage

Usual Adult Dose for Cold Symptoms

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg oral tablet, or
Acetaminophen/diphenhydramine/phenylephrine 325 mg-25 mg-5 mg oral tablet:
2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/15 mL oral syrup:
30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg oral powder for reconstitution (one packet):
one packet dissolved in 8 oz hot water orally every 4 hours; sip while hot. Consume entire drink within 10 to 15 minutes. Do not exceed 6 packets in 24 hours.

Acetaminophen/diphenhydramine/phenylephrine 160 mg-6.25 mg-2.5 mg/5 mL oral liquid:
20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.

Usual Pediatric Dose for Cold Symptoms

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg oral tablet:
12 yrs or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.
6 yrs to 11 yrs: 1 tablet orally every 4 hours not to exceed 5 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-25 mg-5 mg oral tablet:
12 yrs or older: 2 tablets orally every 4 hours not to exceed 12 tablets daily.

Acetaminophen/diphenhydramine/phenylephrine 325 mg-12.5 mg-5 mg/15 mL oral syrup
12 yrs or older: 30 mL orally every 4 hours not to exceed 180 mL daily.

Acetaminophen/diphenhydramine/phenylephrine 650 mg-25 mg-10 mg oral powder for reconstitution (one packet):
12 yrs or older: one packet dissolved in 8 oz hot water orally every 4 hours; sip while hot. Consume entire drink within 10 to 15 minutes. Do not exceed 6 packets in 24 hours.

Acetaminophen/diphenhydramine/phenylephrine 160 mg-6.25 mg-2.5 mg/5 mL oral liquid:
12 yrs or older: 20 mL orally every 4 hours not to exceed 6 doses in any 24 hour period.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dialysis

Data not available

See also...