Thyroid desiccated Disease Interactions

There are 5 disease interactions with thyroid desiccated:

Thyroid Hormones (Includes Thyroid desiccated) ↔ Adrenal Insufficiency

Severe Potential Hazard, High plausibility

Applies to: Adrenal Insufficiency, Panhypopituitarism

The use of thyroid hormones is contraindicated in patients with uncorrected adrenal insufficiency. Thyroid hormones increase tissue demand for adrenocortical hormones and may precipitate acute adrenal crisis. In patients with controlled adrenal insufficiency or other endocrine disorders, therapy for these concomitant disorders may need to be adjusted following thyroid replacement, since hypothyroidism often obscure or diminish the signs and symptoms of these conditions. Clinical monitoring of thyroid and adrenal function as well as any other appropriate endocrine function is recommended during thyroid hormone therapy.

References

  1. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals, St. Louis, MO.
  2. "Product Information. Cytomel (liothyronine)." SmithKline Beecham, Philadelphia, PA.
  3. "Product Information. Armour thyroid (thyroid desiccated)." Forest Pharmaceuticals, St. Louis, MO.
View all 4 references

Thyroid Hormones (Includes Thyroid desiccated) ↔ Cardiovascular Disease

Severe Potential Hazard, High plausibility

Applies to: Hypertension, Heart Disease

Thyroid hormones cause increases in myocardial contractility and heart rate as a result of increased metabolic demands and oxygen consumption. Therapy with thyroid hormones should be administered cautiously and initiated at reduced dosages in patients with cardiovascular disorders such as angina, coronary artery disease, and hypertension. Clinical monitoring of cardiovascular function is recommended. If chest pain or exacerbation of cardiovascular disease occurs, the dosage of thyroid hormone should be reduced, even at the expense of achieving euthyroid state. Thyroid hormones should not be administered to patients with an acute myocardial infarction that is not complicated by hypothyroidism.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
  2. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals, St. Louis, MO.
  3. "Product Information. Armour thyroid (thyroid desiccated)." Forest Pharmaceuticals, St. Louis, MO.
View all 4 references

Thyroid Hormones (Includes Thyroid desiccated) ↔ Thyrotoxicosis

Severe Potential Hazard, High plausibility

Applies to: Hyperthyroidism

The use of thyroid hormones is contraindicated in patients with untreated thyrotoxicosis of any etiology, since thyroid hormones may exacerbate the condition.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
  2. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals, St. Louis, MO.
  3. "Product Information. Cytomel (liothyronine)." SmithKline Beecham, Philadelphia, PA.
View all 4 references

Thyroid Hormones (Includes Thyroid desiccated) ↔ Diabetes

Moderate Potential Hazard, High plausibility

Applies to: Diabetes Insipidus, Diabetes Mellitus

Since hypothyroidism often obscure or diminish the signs and symptoms of endocrine disorders such as diabetes mellitus or diabetes insipidus, thyroid replacement therapy may aggravate the intensity of symptoms associated with these conditions. Patients with endocrine disorders should be monitored more closely during thyroid hormone therapy, and their medication regimen adjusted accordingly. If thyroid medication is later discontinued, a downward readjustment of insulin or oral hypoglycemic agent may be necessary in patients with diabetes mellitus to avoid hypoglycemia.

References

  1. "Product Information. Armour thyroid (thyroid desiccated)." Forest Pharmaceuticals, St. Louis, MO.
  2. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals, St. Louis, MO.
  3. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.
View all 4 references

Thyroid Hormones (Includes Thyroid desiccated) ↔ Seizures

Moderate Potential Hazard, Low plausibility

Applies to: Seizures

Thyroid hormones may alter the seizure threshold. Seizures have been reported rarely following the initiation of levothyroxine therapy. Therapy with thyroid hormones should be administered cautiously in patients predisposed to seizures.

References

  1. "Product Information. Synthroid (levothyroxine)." Abbott Pharmaceutical, Abbott Park, IL.

You should also know about...

thyroid desiccated drug Interactions

There are 549 drug interactions with thyroid desiccated

thyroid desiccated alcohol/food Interactions

There are 3 alcohol/food interactions with thyroid desiccated

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.

Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.

Do not stop taking any medications without consulting your healthcare provider.

Disclaimer: Every effort has been made to ensure that the information provided by Multum is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. Multum's information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill, knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2014 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

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