Thyroid desiccated Disease Interactions
There are 5 disease interactions with thyroid desiccated:
Thyroid Hormones (Includes Thyroid desiccated) ↔ Adrenal Insufficiency
Severe Potential Hazard, High plausibility
Applies to: Adrenal Insufficiency, Panhypopituitarism
The use of thyroid hormones is contraindicated in patients with uncorrected adrenal insufficiency. Thyroid hormones increase tissue demand for adrenocortical hormones and may precipitate acute adrenal crisis. In patients with controlled adrenal insufficiency or other endocrine disorders, therapy for these concomitant disorders may need to be adjusted following thyroid replacement, since hypothyroidism often obscure or diminish the signs and symptoms of these conditions. Clinical monitoring of thyroid and adrenal function as well as any other appropriate endocrine function is recommended during thyroid hormone therapy.
Thyroid Hormones (Includes Thyroid desiccated) ↔ Cardiovascular Disease
Severe Potential Hazard, High plausibility
Applies to: Hypertension, Heart Disease
Thyroid hormones cause increases in myocardial contractility and heart rate as a result of increased metabolic demands and oxygen consumption. Therapy with thyroid hormones should be administered cautiously and initiated at reduced dosages in patients with cardiovascular disorders such as angina, coronary artery disease, and hypertension. Clinical monitoring of cardiovascular function is recommended. If chest pain or exacerbation of cardiovascular disease occurs, the dosage of thyroid hormone should be reduced, even at the expense of achieving euthyroid state. Thyroid hormones should not be administered to patients with an acute myocardial infarction that is not complicated by hypothyroidism.
Thyroid Hormones (Includes Thyroid desiccated) ↔ Thyrotoxicosis
Severe Potential Hazard, High plausibility
Applies to: Hyperthyroidism
The use of thyroid hormones is contraindicated in patients with untreated thyrotoxicosis of any etiology, since thyroid hormones may exacerbate the condition.
Thyroid Hormones (Includes Thyroid desiccated) ↔ Diabetes
Moderate Potential Hazard, High plausibility
Applies to: Diabetes Insipidus, Diabetes Mellitus
Since hypothyroidism often obscure or diminish the signs and symptoms of endocrine disorders such as diabetes mellitus or diabetes insipidus, thyroid replacement therapy may aggravate the intensity of symptoms associated with these conditions. Patients with endocrine disorders should be monitored more closely during thyroid hormone therapy, and their medication regimen adjusted accordingly. If thyroid medication is later discontinued, a downward readjustment of insulin or oral hypoglycemic agent may be necessary in patients with diabetes mellitus to avoid hypoglycemia.
Thyroid Hormones (Includes Thyroid desiccated) ↔ Seizures
Moderate Potential Hazard, Low plausibility
Applies to: Seizures
Thyroid hormones may alter the seizure threshold. Seizures have been reported rarely following the initiation of levothyroxine therapy. Therapy with thyroid hormones should be administered cautiously in patients predisposed to seizures.
You should also know about...
thyroid desiccated drug Interactions
There are 532 drug interactions with thyroid desiccated
thyroid desiccated alcohol/food Interactions
There are 3 alcohol/food interactions with thyroid desiccated
See also...
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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