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Omega-3 polyunsaturated fatty acids Disease Interactions

There are 2 disease interactions with omega-3 polyunsaturated fatty acids.

Moderate

Omega-3 fatty acids (applies to omega-3 polyunsaturated fatty acids) arrhythmias

Moderate Potential Hazard, Moderate plausibility.

Cases of recurrent atrial fibrillation (AF) or flutter have been reported with the use of omega-3 fatty acids in patients with a symptomatic paroxysmal AF or persistent AF. This condition is more apparent within the first 2 to 3 months after the initiation of therapy. Therapy with these agents should be administered cautiously in patients with cardiac conduction disorders.

References

  1. "Product Information. Omacor (omega-3 polyunsaturated fatty acids)." Abbott Pharmaceutical (2005):
Moderate

Omega-3 fatty acids (applies to omega-3 polyunsaturated fatty acids) liver disease

Moderate Potential Hazard, Moderate plausibility.

Increases in alanine aminotransferase (ALT) and/or aspartate aminotransferase (AST) levels have been observed in patients receiving omega-3 fatty acids. Therapy with omega-3 fatty acid preparations should be administered cautiously in patients with hepatic impairment. Serum liver enzyme levels should be monitored periodically.

References

  1. "Product Information. Omacor (omega-3 polyunsaturated fatty acids)." Abbott Pharmaceutical (2005):
  2. "Product Information. Lovaza (omega-3 polyunsaturated fatty acids)." Woodward Pharma Services Rev. 02-2021-00 (2021):

Omega-3 polyunsaturated fatty acids drug interactions

There are 72 drug interactions with omega-3 polyunsaturated fatty acids.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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