Atrovent HFA (ipratropium) Disease Interactions
There is 1 disease interaction with Atrovent HFA (ipratropium):
Ipratropium/Tiotropium (Includes Atrovent HFA) ↔ Anticholinergic Effects
Moderate Potential Hazard, Low plausibility
Applies to: Urinary Retention, Glaucoma (Narrow Angle)
Ipratropium and tiotropium are anticholinergic agents. Although systemic effects are rarely seen due to the poor absorption of quaternary ammonium compounds from gastrointestinal and nasal mucosa, there have been reports of increased intraocular pressure and precipitation or exacerbation of angle-closure glaucoma following inadvertent contact of the eye with aerosolized or nebulized drug. Accordingly, therapy with ipratropium and tiotropium should be administered cautiously in patients with urinary retention/obstruction or angle-closure glaucoma. Measures should be taken to minimize ocular exposure to these drugs (e.g., keeping eyes closed during administration by oral inhalation; use of a mouthpiece rather than face mask during nebulization). Urinary retention has been reported occasionally in patients receiving larger doses of ipratropium by nebulizer.
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Atrovent HFA (ipratropium) drug Interactions
There are 329 drug interactions with Atrovent HFA (ipratropium)
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Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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