Ocufen (flurbiprofen ophthalmic) Disease Interactions
There is 1 disease interaction with Ocufen (flurbiprofen ophthalmic):
Ophthalmic Nsaids (Includes Ocufen) ↔ Platelet Inhibition
Moderate Potential Hazard, Low plausibility
Applies to: Thrombocytopenia, Coagulation Defect, Thrombocytopathy, Bleeding, Vitamin K Deficiency
Topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) are systemically absorbed, with the potential for producing rare but clinically significant systemic effects. NSAIDs have been shown to reversibly inhibit platelet adhesion and aggregation and may slightly prolong bleeding time in healthy individuals. These effects may be more pronounced in patients with underlying hemostatic abnormalities. Thrombocytopenia has also been reported rarely during NSAID use. Therapy with ocular NSAIDs should be administered cautiously in patients with significant active bleeding or a hemorrhagic diathesis, including hemostatic and/or coagulation defects associated with hemophilia, vitamin K deficiency, hypoprothrombinemia, thrombocytopenia, thrombocytopathy, or severe hepatic impairment.
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Ocufen (flurbiprofen ophthalmic) drug Interactions
There are 100 drug interactions with Ocufen (flurbiprofen ophthalmic)
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Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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