Diclofenac ophthalmic Disease Interactions
There is 1 disease interaction with diclofenac ophthalmic:
Ophthalmic Nsaids (Includes Diclofenac ophthalmic) ⇔ Platelet Inhibition
Moderate Potential Hazard, Low plausibility
Applies to: Coagulation Defect, Thrombocytopathy, Thrombocytopenia, Bleeding, Vitamin K Deficiency
Topically applied nonsteroidal anti-inflammatory drugs (NSAIDs) are systemically absorbed, with the potential for producing rare but clinically significant systemic effects. NSAIDs have been shown to reversibly inhibit platelet adhesion and aggregation and may slightly prolong bleeding time in healthy individuals. These effects may be more pronounced in patients with underlying hemostatic abnormalities. Thrombocytopenia has also been reported rarely during NSAID use. Therapy with ocular NSAIDs should be administered cautiously in patients with significant active bleeding or a hemorrhagic diathesis, including hemostatic and/or coagulation defects associated with hemophilia, vitamin K deficiency, hypoprothrombinemia, thrombocytopenia, thrombocytopathy, or severe hepatic impairment.
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diclofenac ophthalmic drug Interactions
There are 95 drug interactions with diclofenac ophthalmic
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