Zyrtec (cetirizine) Disease Interactions
There is 1 disease interaction with Zyrtec (cetirizine):
Cetirizine (Includes Zyrtec) ⇔ Renal/Liver Disease
Moderate Potential Hazard, High plausibility
Applies to: Renal Dysfunction, Liver Disease
Cetirizine is eliminated primarily by the kidney but also undergoes metabolism in the liver to some extent. Patients with renal and/or liver disease may be at greater risk for adverse effects from cetirizine due to decreased drug clearance. The manufacturer recommends an initial dosage of 5 mg once daily in patients 6 years of age and older with decreased renal function (CrCl <= 30 mL/min, including those on hemodialysis) and/or impaired hepatic function. Cetirizine should preferably not be used in children less than 6 years of age with renal and/or hepatic impairment because of the difficulty in reliably administering doses smaller than 2.5 mg (1/2 teaspoonful) and a lack of pharmacokinetic and safety data in this population.
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Zyrtec (cetirizine) drug Interactions
There are 572 drug interactions with Zyrtec (cetirizine)
Zyrtec (cetirizine) food/lifestyle Interactions
There is 1 food/lifestyle interaction with Zyrtec (cetirizine)
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