Pulmicort Turbuhaler (budesonide) Disease Interactions

There are 5 disease interactions with Pulmicort Turbuhaler (budesonide):

Inhaled Corticosteroids (Includes Pulmicort Turbuhaler) ↔ Hyperadrenocorticism

Moderate Potential Hazard, Moderate plausibility

Applies to: Hyperadrenocorticism

The use of inhaled and nasal corticosteroids may rarely precipitate or aggravate conditions of hyperadrenocorticism. Although adverse effects of corticosteroids may be minimized by local rather than systemic administration, the risks are not entirely abolished. Inhaled and nasally applied drug may be absorbed into the circulation, especially when large doses are used. It is important that the recommended dosages of the individual products not be exceeded and that the lowest effective dosage be used. The development of symptoms such as menstrual irregularities, acneiform lesions, cataracts and cushingoid features during inhaled or nasal corticosteroid therapy may indicate excessive use.

Inhaled Corticosteroids (Includes Pulmicort Turbuhaler) ↔ Infections

Moderate Potential Hazard, Moderate plausibility

Applies to: Infection - Bacterial/Fungal/Protozoal/Viral, Tuberculosis -- Latent

The immunosuppressant and anti-inflammatory effects of corticosteroids, particularly in higher dosages, may decrease host resistance to infectious agents, decrease the ability to localize infections, and mask the symptoms of infection. Secondary infections may be more likely to develop. Therapy with inhaled and nasal corticosteroids should be administered cautiously in patients with an infection, particularly active or quiescent tuberculosis infection of the respiratory tract or any untreated systemic fungal, bacterial, parasitic, or viral infection. Although adverse effects of corticosteroids may be minimized by local rather than systemic administration, the risks are not entirely abolished. Inhaled and nasally applied drug may be absorbed into the circulation, especially when large doses are used. It is important that the recommended dosages of the individual products not be exceeded and that the lowest effective dosage be used.

Inhaled Corticosteroids (Includes Pulmicort Turbuhaler) ↔ Ocular Herpes Simplex

Moderate Potential Hazard, Moderate plausibility

Applies to: Ocular Herpes Simplex

Pharmacologic dosages of corticosteroids may increase the risk of corneal perforation in patients with ocular herpes simplex. Therapy with inhaled and nasal corticosteroids should be administered cautiously in such patients.

Inhaled Corticosteroids (Includes Pulmicort Turbuhaler) ↔ Ocular Toxicities

Moderate Potential Hazard, Low plausibility

Applies to: Glaucoma/Intraocular Hypertension, Cataracts

Prolonged use of corticosteroids may cause posterior subcapsular cataracts and elevated intraocular pressure, the latter of which may lead to glaucoma and/or damage to the optic nerves. Therapy with inhaled and nasal corticosteroids has only rarely produced these effects but should be administered cautiously nonetheless in patients with a history of cataracts, glaucoma, or increased intraocular pressure. Although adverse effects of corticosteroids may be minimized by local rather than systemic administration, the risks are not entirely abolished. Inhaled and nasally applied drug may be absorbed into the circulation, especially when large doses are used. It is important that the recommended dosages of the individual products not be exceeded and that the lowest effective dosage be used.

Inhaled Corticosteroids (Includes Pulmicort Turbuhaler) ↔ Osteoporosis

Moderate Potential Hazard, Moderate plausibility

Applies to: Osteoporosis

Prolonged use of inhaled corticosteroids may be associated with a reduction in bone density. This effect appears to be dose-related and has been reported primarily with high dosages (>= 800 mcg/day of beclomethasone or equivalent for >= 1 year). Reduced levels of total body calcium have also been demonstrated in patients receiving lower dosages. Long-term therapy with inhaled and nasal corticosteroids should be administered cautiously in patients with osteoporosis. It is important that the recommended dosages of the individual products not be exceeded and that the lowest effective dosage be used.

You should also know about...

Pulmicort Turbuhaler (budesonide) drug Interactions

There are 364 drug interactions with Pulmicort Turbuhaler (budesonide)

Pulmicort Turbuhaler (budesonide) alcohol/food Interactions

There is 1 alcohol/food interaction with Pulmicort Turbuhaler (budesonide)

See also...

• Side Effects of Pulmicort Turbuhaler (budesonide)
• Pulmicort Turbuhaler (budesonide) Consumer Information

• Drug Interactions Checker

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