Medical Term:

X-linked lymphoproliferative syndrome

 

Definition: an X-linked recessive immunodeficiency and lymphoproliferative disease caused by mutation in the SH2 domain protein 1A gene (SH2D1A) on Xq; characterized by defective cellular or humoral immune response to Epstein-Barr virus; manifestations include fulminant infectious mononucleosis, B-cell malignancies, and hypogammaglobulinemia.

Synonym(s): Duncan disease, Duncan syndrome, lymphoproliferative syndrome, X-linked lymphoproliferative disease

Hide
(web4)