Pronunciation: vulf chī′kof
Definition: obstruction of the organic binding of iodine and its incorporation into hormone, caused by large doses of iodine; usually transient, but in large doses in susceptible people, the effect can be prolonged and cause iodine myxedema.
Synonym(s): Wolff-Chaikoff effect
[Louis Wolff; Israel Chaikoff]
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Examples: glitazone, GI cocktail, etc.