- The act of removal or retreat.
- A psychological and/or physical syndrome caused by the abrupt cessation of the use of a drug in an habituated person.
- The therapeutic process of discontinuing a drug to avoid the symptoms of withdrawal (2).
- A pattern of behavior observed in schizophrenia and depression, characterized by a pathologic retreat from interpersonal contact and social involvement and leading to self-preoccupation.
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Examples: glitazone, GI cocktail, etc.