Medical Term:
Waldenström macroglobulinemia
Pronunciation: vahld′ĕn-strum
Definition: macroglobulinemia occurring in old people, characterized by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anemia, increased sedimentation rate, and hyperglobulinemia with a narrow peak in γ-globulin or β2-globulin at about 19 S units. The spleen, liver, or lymph nodes are often enlarged with frequent purpura or mucosal bleeding.
Synonym(s): hyperglobulinemic purpura, Waldenström purpura, Waldenström syndrome
