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Pronunciation: ŭn-kŭp′lĕrz
Definition: Substances such as dinitrophenol that allow oxidation in mitochondria to proceed without the usual concomitant phosphorylation to produce ATP; these poisons thus “uncouple” oxidation and phosphorylation.
Synonym(s): uncoupling factors
Examples: glitazone, GI cocktail, etc.
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