Medical Term:
trimethoprim-sulfamethoxazole
Pronunciation: trī-meth′ō-prim sŭl′fă-meth-oks′ă-zōl
Definition: A drug combination consisting of a dihydrofolate reductase inhibitor (trimethoprim) and a sulfonamide antibacterial drug (sulfamethoxazole). The drug combination is synergistic as the drugs interfere with two successive steps in the formation/utilization of folic acid by microorganisms. Used to treat many infectious diseases.
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Examples: glitazone, GI cocktail, etc.
