Medical Term:
succinyl-CoA synthetase
Definition:
- a ligase reversibly reacting succinate and CoA with ATP to produce ADP, inorganic phosphate, and succinyl-CoA;
- a similar synthetase, but one able to use itaconate as well as succinate and GTP (or ITP) in place of ATP; a part of the tricarboxylic acid cycle.
Synonym(s): succinate:CoA ligase, succinate:CoA ligase, succinic thiokinase
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Examples: glitazone, GI cocktail, etc.
